Effect of bovine colostrum supplementation on gut health of children: A systematic review.

IF 2.4 3区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2025-06-01 Epub Date: 2025-03-27 DOI:10.1002/jpn3.70033

Deshna Oswal, Mubashir Angolkar, N S Mahantashetti, Pooja Dhagavkar, Shivani Haritay, Madan Godbole

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引用次数: 0

Abstract

Objective: This study aimed to assess the impact of bovine colostrum (BC) on the gut health of the pediatric population.

Methodology: The systematic review was conducted in accordance with Preferred Reporting Items for Systematic Review and Meta-analysis guidelines 2020. Full-text articles such as randomized control trials, cohort prospective studies, and pilot studies were identified from the following databases: PubMed, Web of Science, ProQuest, Clinicaltrial.gov, and Cochrane. After assessing for inclusion and exclusion criteria, eight studies were finally included and assessed for quality using the Effective Public Health Practice Project scale.

Results: Some studies reported a positive impact of BC on the duration and frequency of diarrheal infection in children, but the overall clinical benefits of BC in the gut health of children remain inconclusive. The studies were heterogeneous with regard to methodology, dose, form of BC used, and outcomes studied; hence, a meta-analysis could not be performed in terms of outcomes assessed.

Conclusion: No conclusion can be drawn regarding the clinical benefits of BC in the gut health of children. Further studies are needed in the pediatric population using BC as an intervention for a variety of gastro-intestinal problems.

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补充牛初乳对儿童肠道健康的影响：一项系统综述。

目的：本研究旨在评估牛初乳（BC）对儿童肠道健康的影响。方法：系统评价按照2020年系统评价和荟萃分析指南的首选报告项目进行。全文文章，如随机对照试验、队列前瞻性研究和试点研究，从以下数据库中确定：PubMed、Web of Science、ProQuest、Clinicaltrial.gov和Cochrane。在评估纳入和排除标准后，最终纳入了8项研究，并使用有效公共卫生实践项目量表对其质量进行了评估。结果：一些研究报道了BC对儿童腹泻感染的持续时间和频率的积极影响，但BC对儿童肠道健康的总体临床益处仍不确定。这些研究在方法学、剂量、使用的BC形式和研究结果方面存在异质性；因此，就评估的结果而言，不能进行荟萃分析。结论：BC对儿童肠道健康的临床益处尚未得出结论。在儿童人群中使用BC作为各种胃肠道问题的干预还需要进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pediatric Gastroenterology and Nutrition 医学-胃肠肝病学

CiteScore

5.30

自引率

13.80%

发文量

467

审稿时长

3-6 weeks

期刊介绍： The Journal of Pediatric Gastroenterology and Nutrition (JPGN) provides a forum for original papers and reviews dealing with pediatric gastroenterology and nutrition, including normal and abnormal functions of the alimentary tract and its associated organs, including the salivary glands, pancreas, gallbladder, and liver. Particular emphasis is on development and its relation to infant and childhood nutrition.