Early Detection of Local Recurrence After Rectal Cancer Resection in Asymptomatic Patients Is Essential for Survival.

IF 2 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2025-03-28 DOI:10.1002/jso.28120

Katharina Esswein, Eva Hummer, Marijana Ninkovic, Elisabeth Gasser, Veronika Kröpfl, Reinhold Kafka-Ritsch

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引用次数: 0

Abstract

Background and objectives: Despite advancements in rectal cancer treatment, therapy of local recurrence remains a significant challenge as it has to be individualized to the extent of recurrence and prior treatment. This study aims to analyze outcomes of patients with local recurrence after resection for rectal cancer, focusing on R0-resection rates and overall survival (OS).

Methods: A retrospective cohort study included 31 patients with local recurrence after initial curative resection for rectal cancer between 2003 and 2021.

Results: Recurrence was diagnosed in 77.4% of cases during scheduled routine follow-up and 58,1% of patients reported of symptoms at the time of diagnosis. Symptomatic patients tended to be treated palliatively (66.7%, 12/18, p = 0.073). A curative treatment approach was intended in 48.4% of all patients, with 80% achieving R0-resection by surgery. The 5-year OS was significantly longer in patients achieving R0-resection (58.3% vs. 5.3%, p = 0.0) and decreased in symptomatic patients (11.1% vs. 46.2%, p = 0.025).

Conclusions: These findings emphasize the importance of early recurrence detection, optimally in a scheduled cancer follow-up.

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早期检测无症状患者直肠癌切除术后的局部复发对生存至关重要

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来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.