Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region.

IF 4.5 2区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Journal for Equity in Health Pub Date : 2025-03-27 DOI:10.1186/s12939-025-02448-9

Omar Al Ta'ani, Yazan Al-Ajlouni, Chloe Lahoud, Sharifeh Almasaid, Yahya Alhalalmeh, Zaid Oweis, Pojsakorn Danpanichkul, Ali Baidoun, Saqr Alsakarneh, Dushyant Singh Dahiya, Basile Njei

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引用次数: 0

Abstract

Introduction: Digestive diseases (DD) pose a significant global health burden, with the Middle East and North Africa (MENA) region providing a unique landscape to study the impact of socioeconomic disparities on DD incidence and outcomes. This study examines the burden of DD in the MENA region, focusing on socioeconomic influences.

Methods: We utilized data from the Global Burden of Disease (GBD) dataset from 1990 to 2021, analyzing trends in incidence, mortality, and disability-adjusted life years (DALYs) for DD. Percentage changes and estimated annual percentage changes (EAPCs) were calculated for age-standardized rates, and correlations were assessed between disease metrics and socio-demographic indices, including the Socio-demographic Index (SDI), Human Development Index (HDI), and Gender Inequality Index (GII).

Results: Between 1990 and 2021, the total incidence of DD rose by 129.8%, from 19.7 million to 45.4 million cases. Age-standardized mortality and DALY rates decreased by 48.3% and 44.7%, respectively. Strong correlations were observed between age-standardized incidence rates (ASIR) and SDI (r = 0.90), HDI (r = 0.88), and GII (r = - 0.86). EAPCs for incidence, deaths, and DALYs were 0.79, -2.29, and - 1.88, respectively.

Conclusion: Despite a reduction in mortality and DALY rates, the persistently high incidence rates of DD in the MENA region underscores ongoing public health challenges. Socioeconomic factors strongly influence disease burden, highlighting the need for targeted interventions to address disparities and improve digestive disease outcomes across the region.

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中东和北非地区消化系统疾病影响的社会经济和人口差异

消化系统疾病（DD）构成了重大的全球健康负担，中东和北非（MENA）地区为研究社会经济差异对DD发病率和结局的影响提供了独特的环境。本研究考察了中东和北非地区DD的负担，重点关注社会经济影响。方法：利用1990年至2021年全球疾病负担（GBD）数据集的数据，分析DD的发病率、死亡率和残疾调整生命年（DALYs）的趋势，计算年龄标准化率的百分比变化和估计年百分比变化（EAPCs），并评估疾病指标与社会人口指标(包括社会人口指数（SDI）、人类发展指数（HDI）和性别不平等指数（GII）之间的相关性。结果：1990年至2021年，DD总发病率从1970万例上升到4540万例，上升了129.8%。年龄标准化死亡率和DALY分别下降48.3%和44.7%。年龄标准化发病率（ASIR）与SDI （r = 0.90）、HDI （r = 0.88）和GII （r = - 0.86）有很强的相关性。发病率、死亡率和DALYs的EAPCs分别为0.79、-2.29和- 1.88。结论：尽管死亡率和伤残残疾率有所下降，但中东和北非地区DD的持续高发病率凸显了持续存在的公共卫生挑战。社会经济因素对疾病负担有很大影响，强调需要采取有针对性的干预措施，以解决该地区的差异并改善消化系统疾病的结局。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal for Equity in Health Medicine-Health Policy

CiteScore

7.80

自引率

4.20%

发文量

162

审稿时长

28 weeks

期刊介绍： International Journal for Equity in Health is an Open Access, peer-reviewed, online journal presenting evidence relevant to the search for, and attainment of, equity in health across and within countries. International Journal for Equity in Health aims to improve the understanding of issues that influence the health of populations. This includes the discussion of political, policy-related, economic, social and health services-related influences, particularly with regard to systematic differences in distributions of one or more aspects of health in population groups defined demographically, geographically, or socially.