Maciej T Wybraniec, Fabian Wesołek, Przemysław Szyszka, Małgorzata Cichoń, Michał Orszulak, Magdalena Mizia-Szubryt, Michał Wita, Monika Gawałko, Monika Budnik, Beata Uziębło-Życzkowska, Paweł Krzesiński, Katarzyna Starzyk, Beata Wożakowska-Kapłon, Ludmiła Daniłowicz-Szymanowicz, Damian Kaufmann, Maciej Wójcik, Robert Błaszczyk, Jarosław Hiczkiewicz, Jan Budzianowski, Katarzyna Łojewska, Katarzyna Kosmalska, Marcin Fijałkowski, Anna Szymańska, Anna Wiktorska, Maciej Haberka, Michał Kucio, Błażej Michalski, Karolina Kupczyńska, Anna Tomaszuk-Kazberuk, Katarzyna Wilk-Śledziewska, Renata Wachnicka-Truty, Marek Koziński, Paweł Burchardt, Katarzyna Mizia-Stec, Agnieszka Kapłon-Cieślicka
{"title":"Prevalence of Left Atrial Thrombus in Patients with Atrial Flutter in Comparison to Atrial Fibrillation.","authors":"Maciej T Wybraniec, Fabian Wesołek, Przemysław Szyszka, Małgorzata Cichoń, Michał Orszulak, Magdalena Mizia-Szubryt, Michał Wita, Monika Gawałko, Monika Budnik, Beata Uziębło-Życzkowska, Paweł Krzesiński, Katarzyna Starzyk, Beata Wożakowska-Kapłon, Ludmiła Daniłowicz-Szymanowicz, Damian Kaufmann, Maciej Wójcik, Robert Błaszczyk, Jarosław Hiczkiewicz, Jan Budzianowski, Katarzyna Łojewska, Katarzyna Kosmalska, Marcin Fijałkowski, Anna Szymańska, Anna Wiktorska, Maciej Haberka, Michał Kucio, Błażej Michalski, Karolina Kupczyńska, Anna Tomaszuk-Kazberuk, Katarzyna Wilk-Śledziewska, Renata Wachnicka-Truty, Marek Koziński, Paweł Burchardt, Katarzyna Mizia-Stec, Agnieszka Kapłon-Cieślicka","doi":"10.1016/j.hrthm.2025.03.1980","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Atrial flutter (AFL) and atrial fibrillation (AF) are believed to carry the same risk of systemic thromboembolism however there is paucity of data concerning such risk in patients with AFL in comparison to AF.</p><p><strong>Objective: </strong>The aim of the study was to evaluate the prevalence of left atrial thrombus (LAT) on transesophageal echocardiography (TEE) in patients with AFL in comparison to AF depending on anticoagulation status.</p><p><strong>Methods: </strong>The study is the sub-analysis of a multicenter, prospective Left Atrial Thrombus on Transesophageal Echocardiography (LATTEE) registry, which enrolled AF and AFL patients referred for ablation or electrical cardioversion regardless of oral anticoagulation (OAC) use. All patients underwent pre-procedural TEE to assess the primary endpoint of the LAT presence.</p><p><strong>Results: </strong>A total of 3109 patients (AF n=2577; AFL n=532) were included in the study. Therapeutic OAC, defined as anticoagulation lasting at least three weeks, was used by 89.8% of patients in the AF subgroup and 82.5% in the AFL subgroup (p<0.001). LAT was present in 8.3% of patients with AF and 6.8% with AFL, regardless of therapeutic OAC use (p=0.235). In patients on therapeutic OAC, LAT was present in 7.6% in AF group and 5.7% in AFL subgroup (p=0.167), while in patients without therapeutic OAC in 14.9% in AF subgroup and 11.8% in AFL subgroup (p=0.459).</p><p><strong>Conclusion: </strong>The risk of thrombus formation in AFL seems to be similar to AF, supporting similar recommendations concerning OAC use.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart rhythm","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.hrthm.2025.03.1980","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Atrial flutter (AFL) and atrial fibrillation (AF) are believed to carry the same risk of systemic thromboembolism however there is paucity of data concerning such risk in patients with AFL in comparison to AF.
Objective: The aim of the study was to evaluate the prevalence of left atrial thrombus (LAT) on transesophageal echocardiography (TEE) in patients with AFL in comparison to AF depending on anticoagulation status.
Methods: The study is the sub-analysis of a multicenter, prospective Left Atrial Thrombus on Transesophageal Echocardiography (LATTEE) registry, which enrolled AF and AFL patients referred for ablation or electrical cardioversion regardless of oral anticoagulation (OAC) use. All patients underwent pre-procedural TEE to assess the primary endpoint of the LAT presence.
Results: A total of 3109 patients (AF n=2577; AFL n=532) were included in the study. Therapeutic OAC, defined as anticoagulation lasting at least three weeks, was used by 89.8% of patients in the AF subgroup and 82.5% in the AFL subgroup (p<0.001). LAT was present in 8.3% of patients with AF and 6.8% with AFL, regardless of therapeutic OAC use (p=0.235). In patients on therapeutic OAC, LAT was present in 7.6% in AF group and 5.7% in AFL subgroup (p=0.167), while in patients without therapeutic OAC in 14.9% in AF subgroup and 11.8% in AFL subgroup (p=0.459).
Conclusion: The risk of thrombus formation in AFL seems to be similar to AF, supporting similar recommendations concerning OAC use.
期刊介绍:
HeartRhythm, the official Journal of the Heart Rhythm Society and the Cardiac Electrophysiology Society, is a unique journal for fundamental discovery and clinical applicability.
HeartRhythm integrates the entire cardiac electrophysiology (EP) community from basic and clinical academic researchers, private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our EP community.
The Heart Rhythm Society is the international leader in science, education, and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorders. Its mission is to improve the care of patients by promoting research, education, and optimal health care policies and standards.