Inflammatory Markers and Postoperative New-Onset Atrial Fibrillation: Prognostic Predictions of Neutrophil Percent to Albumin Ratio in Patients with CABG.

IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Faruk Serhatlioglu, Yucel Yilmaz, Oguzhan Baran, Halis Yilmaz, Saban Kelesoglu
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引用次数: 0

Abstract

Background/Objectives: Postoperative new-onset atrial fibrillation (AF) (PNOAF) is the most common complication after coronary artery bypass graft (CABG), and its incidence has been reported as up to 50% in studies. In this study, we investigated whether there was a relationship between PNOAF and the neutrophil percentage to albumin ratio (NPAR) levels after on-pump CABG. Methods: A total of 454 patients who underwent CABG were included in the study. NPAR was calculated by dividing the neutrophil count by the albumin value. Results: It was determined that 93 patients developed PNOAF (20.4%). When the patient groups that developed and did not develop PNOAF were compared in terms of laboratory findings, C-reactive protein (CRP) values (4.0 mg/L (2.8-7.9) vs. 2.9 mg/L (1.1-6.7), <0.001), neutrophil/lymphocyte ratio (NLR) (2.2 (1.2-4.2) vs. 1.4 (0.7-3.1), <0.001), platelets-to-lymphocyte ratio (112 (72-177) vs. 92 (69-122), <0.001) and NPAR (2.29 (1.68-3.8) vs. 1.09 (0.79-1.81), <0.001), were found to be statistically significantly higher in the group that developed PNOAF. ROC analysis showed that the cut-off value for NPAR for the development of PNOAF was 1.86 with 78% sensitivity and 72% specificity (area under the ROC curve = 0.778, 95% CI (0.728-0.828), p < 0.001). Conclusions: NPAR, which can be detected by a simple venous blood test, has shown a strong predictive value for PNOAF in patients with CABG.

背景/目的:术后新发心房颤动(AF)(PNOAF)是冠状动脉旁路移植术(CABG)后最常见的并发症,有研究报道其发生率高达 50%。在本研究中,我们探讨了 PNOAF 与经泵 CABG 术后中性粒细胞百分比与白蛋白比值(NPAR)水平之间是否存在关系。研究方法研究共纳入了 454 名接受 CABG 的患者。NPAR通过中性粒细胞计数除以白蛋白值计算得出。结果确定有 93 例患者(20.4%)发生了 PNOAF。将发生和未发生 PNOAF 的患者组进行实验室结果比较,C 反应蛋白 (CRP) 值(4.0 mg/L (2.8-7.9) vs. 2.9 mg/L (1.1-6.7),P < 0.001)。结论NPAR 可通过简单的静脉血液检测进行检测,对 CABG 患者的 PNOAF 有很强的预测价值。
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来源期刊
Diagnostics
Diagnostics Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
4.70
自引率
8.30%
发文量
2699
审稿时长
19.64 days
期刊介绍: Diagnostics (ISSN 2075-4418) is an international scholarly open access journal on medical diagnostics. It publishes original research articles, reviews, communications and short notes on the research and development of medical diagnostics. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodological details must be provided for research articles.
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