Risk Factors and Dental Caries Incidence in Childhood Cancer Survivors.

IF 4.5 2区 医学 Q1 ONCOLOGY
Cancers Pub Date : 2025-03-17 DOI:10.3390/cancers17061003
Anna Jodłowska, Danuta Ilczuk-Rypuła
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引用次数: 0

Abstract

Background/objectives: Dental caries is believed to be one of the most frequent dental long-term adverse effects of anticancer therapy. It may occur due to numerous chemotherapy-dependent oral symptoms or due to the possible neglection of oral care because of parental involvement in the monitoring of other long-term effects of the therapy. This study aimed to determine the incidence of dental caries and the impact of other risk factors in cancer survivors and age-matched controls.

Methods: This cross-sectional study was conducted on 40 cancer survivors and 80 peers divided into three age groups. Indices such as dmft/s, DMFT/S, ft/s, FT/S, Plaque Index (PI), and Gingival Index (GI) were calculated to compare the study participants. The sum of dmft and DMFT was used to assess the possible impact of socioeconomic, oral hygiene, and dietary factors.

Results: Caries frequency was found to be lower in cancer survivors (92.50%) than in controls (97.50%). No statistically significant differences were found between the study groups within all the caries indices examined. Strong positive correlations with PI and cariogenic diet in the youngest survivors and with PI in middle-aged survivors were observed. Strong negative correlations in middle-aged children were noticed in terms of father's education in survivors and mother's education in controls.

Conclusions: The study findings suggest that there is no relationship between chemotherapy and dental caries in long-term cancer survivors. Careful dental care still remains a major contributor to maintaining oral health.

儿童癌症幸存者的风险因素和龋齿发病率。
背景/目的:龋齿被认为是抗癌治疗中最常见的牙齿长期不良反应之一。它可能是由于许多化疗依赖的口腔症状或由于父母参与监测治疗的其他长期影响而可能忽视口腔护理而发生的。本研究旨在确定龋齿的发病率和其他危险因素对癌症幸存者和年龄匹配对照的影响。方法:对40名癌症幸存者和80名同龄人进行横断面研究,分为三个年龄组。计算dmft/s、dmft/s、ft/s、ft/s、菌斑指数(PI)和牙龈指数(GI)等指标来比较研究参与者。dmft和dmft的总和用于评估社会经济、口腔卫生和饮食因素可能产生的影响。结果:癌症幸存者龋齿发生率(92.50%)低于对照组(97.50%)。在所有检查的龋齿指数中,研究组之间没有发现统计学上的显著差异。在最年轻的幸存者和中年幸存者中,观察到PI和龋齿饮食有很强的正相关。在中年儿童中,幸存者的父亲受教育程度与对照组的母亲受教育程度呈显著负相关。结论:研究结果表明,长期癌症幸存者的化疗与龋齿之间没有关系。仔细的牙齿护理仍然是保持口腔健康的主要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancers
Cancers Medicine-Oncology
CiteScore
8.00
自引率
9.60%
发文量
5371
审稿时长
18.07 days
期刊介绍: Cancers (ISSN 2072-6694) is an international, peer-reviewed open access journal on oncology. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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