Investigation of cognitive functions in patients with rosacea: a case–control study

IF 1.8 4区 医学 Q3 DERMATOLOGY
Dilek Menteşoğlu, Gökçe Işıl Kurmuş, Selda Pelin Kartal, Ayşe Gökçen Gündoğmuş
{"title":"Investigation of cognitive functions in patients with rosacea: a case–control study","authors":"Dilek Menteşoğlu,&nbsp;Gökçe Işıl Kurmuş,&nbsp;Selda Pelin Kartal,&nbsp;Ayşe Gökçen Gündoğmuş","doi":"10.1007/s00403-025-04173-3","DOIUrl":null,"url":null,"abstract":"<div><p>Rosacea is a chronic inflammatory skin disease and the most prevalent cause of facial redness in adults. It is also associated with various systemic conditions. This study aimed to evaluate cognitive function in patients with rosacea and compare it to healthy controls. A total of 119 individuals, comprising 58 patients with rosacea and 61 controls, were enrolled between April 2023 and September 2024. The Trail Making Test (TMT) was administered to all the participants to assess their cognitive function. In rosacea patients, TMT Part A was 37.9 ± 4.38, and TMT Part B was 73.4 ± 13.28. In the control group, TMT Part A was 38.5 ± 4.86, and TMT Part B was 72.0 ± 9.34 (p = 0.57, p = 0.47, respectively). Based on rosacea severity, the patients were categorized as mild to moderate (n = 35) and severe to very severe (n = 23). There was no significant difference between these groups in TMT Part A and TMT Part B (p = 0.97, p = 0.24, respectively). In addition, according to the rosacea subtype, there was no difference between the groups in TMT Part A, TMT Part B, and years of education (p = 0.58, p = 0.89, and p = 0.20, respectively). Since rosacea may be associated with neurodegenerative diseases, such as Alzheimer’s disease, dementia, and Parkinson’s disease, TMT can be used to investigate cognitive functions.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Dermatological Research","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00403-025-04173-3","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Rosacea is a chronic inflammatory skin disease and the most prevalent cause of facial redness in adults. It is also associated with various systemic conditions. This study aimed to evaluate cognitive function in patients with rosacea and compare it to healthy controls. A total of 119 individuals, comprising 58 patients with rosacea and 61 controls, were enrolled between April 2023 and September 2024. The Trail Making Test (TMT) was administered to all the participants to assess their cognitive function. In rosacea patients, TMT Part A was 37.9 ± 4.38, and TMT Part B was 73.4 ± 13.28. In the control group, TMT Part A was 38.5 ± 4.86, and TMT Part B was 72.0 ± 9.34 (p = 0.57, p = 0.47, respectively). Based on rosacea severity, the patients were categorized as mild to moderate (n = 35) and severe to very severe (n = 23). There was no significant difference between these groups in TMT Part A and TMT Part B (p = 0.97, p = 0.24, respectively). In addition, according to the rosacea subtype, there was no difference between the groups in TMT Part A, TMT Part B, and years of education (p = 0.58, p = 0.89, and p = 0.20, respectively). Since rosacea may be associated with neurodegenerative diseases, such as Alzheimer’s disease, dementia, and Parkinson’s disease, TMT can be used to investigate cognitive functions.

酒渣鼻患者认知功能的调查:一项病例对照研究
酒渣鼻是一种慢性炎症性皮肤病,是成年人面部发红的最常见原因。它还与各种系统状况有关。本研究旨在评估酒渣鼻患者的认知功能,并将其与健康对照进行比较。在2023年4月至2024年9月期间,共有119人,包括58名酒渣鼻患者和61名对照组。研究人员对所有参与者进行了造径测试(TMT)以评估其认知功能。酒渣鼻患者TMT A部分为37.9±4.38,TMT B部分为73.4±13.28。对照组TMT A部分评分为38.5±4.86,TMT B部分评分为72.0±9.34 (p = 0.57, p = 0.47)。根据酒渣鼻的严重程度,将患者分为轻度至中度(n = 35)和重度至极重度(n = 23)。两组间TMT A部分和TMT B部分比较,差异均无统计学意义(p = 0.97, p = 0.24)。此外,根据酒渣鼻亚型,TMT A部分、TMT B部分、受教育年限组间差异无统计学意义(p = 0.58、p = 0.89、p = 0.20)。由于酒渣鼻可能与神经退行性疾病有关,如阿尔茨海默病、痴呆和帕金森病,TMT可用于研究认知功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.10
自引率
3.30%
发文量
30
审稿时长
4-8 weeks
期刊介绍: Archives of Dermatological Research is a highly rated international journal that publishes original contributions in the field of experimental dermatology, including papers on biochemistry, morphology and immunology of the skin. The journal is among the few not related to dermatological associations or belonging to respective societies which guarantees complete independence. This English-language journal also offers a platform for review articles in areas of interest for dermatologists and for publication of innovative clinical trials.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信