Praveen Balakrishnan, Abhayadev A, Emy S. Surendran, Lisha S. Raj
{"title":"Acute urinary retention following frequent administration of Guggulu Tiktakam Kwatha and its management - a case report","authors":"Praveen Balakrishnan, Abhayadev A, Emy S. Surendran, Lisha S. Raj","doi":"10.1016/j.jaim.2024.101086","DOIUrl":null,"url":null,"abstract":"<div><div>A 72-year-old male patient, a diagnosed case of infective spondylodiscitis, was admitted in our hospital for severe pain in the right hip and lower back (in the lumbo-sacral region) in a non-ambulatory mode. Considering the criticality, we administered <em>Kwatha</em> in a <em>Muhurmuhu</em> (frequent administration) schedule. The initial medicines reduced pain, but not the elevated C-reactive protein (CRP). To reduce this elevated CRP, we administered <em>Amruthotharam Kwatha</em> and <em>Guggulu Tiktakam Kwatha</em> (GTK) in the dosage of 30 ml every 2 h for eight times. CRP started reducing, but we encountered an acute urinary retention as an adverse drug reaction. Naranjo Adverse Drug Reaction Probability Scale recording gave a score of eight, which shows that the AE could be probably due to administration of <em>Guggulu Tiktakam Kwatha</em> (GTK) in <em>Muhurmuhu</em> schedule. When the patient did not void urine for more than 6 hours, we did <em>Marma</em> therapy on left <em>Mootthira Kala Marma</em>. The patient voided urine within half an hour of <em>Marma</em> therapy. Clinically, after the medications, pain reduced considerably, CRP came to normal, and the patient came to an ambulatory mode. This case report shows that medicines like GTK should cautiously be administered, as it may complicate. This case report also focusses light on the fact that <em>Marma</em> therapy could be a possible mode of tackling acute conditions.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101086"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ayurveda and Integrative Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0975947624002018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
A 72-year-old male patient, a diagnosed case of infective spondylodiscitis, was admitted in our hospital for severe pain in the right hip and lower back (in the lumbo-sacral region) in a non-ambulatory mode. Considering the criticality, we administered Kwatha in a Muhurmuhu (frequent administration) schedule. The initial medicines reduced pain, but not the elevated C-reactive protein (CRP). To reduce this elevated CRP, we administered Amruthotharam Kwatha and Guggulu Tiktakam Kwatha (GTK) in the dosage of 30 ml every 2 h for eight times. CRP started reducing, but we encountered an acute urinary retention as an adverse drug reaction. Naranjo Adverse Drug Reaction Probability Scale recording gave a score of eight, which shows that the AE could be probably due to administration of Guggulu Tiktakam Kwatha (GTK) in Muhurmuhu schedule. When the patient did not void urine for more than 6 hours, we did Marma therapy on left Mootthira Kala Marma. The patient voided urine within half an hour of Marma therapy. Clinically, after the medications, pain reduced considerably, CRP came to normal, and the patient came to an ambulatory mode. This case report shows that medicines like GTK should cautiously be administered, as it may complicate. This case report also focusses light on the fact that Marma therapy could be a possible mode of tackling acute conditions.