Intramedullary Spinal Cord Metastasis in Spinal Ependymomas.

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI:10.47391/JPMA.25-22

Zanib Javed, Raheema Sadiq, Hania Fatima, Muhammad Shahzad Shamim

引用次数: 0

Abstract

Drop metastasis, or intramedullary spinal cord metastasis (ISCM), is a rare condition accounting 0.9%-5% of CNS or spinal metastases. It arises from tumour cell dissemination through cerebrospinal fluid (CSF), often affecting the thoracic and lumbar spine. Clinical features include rapidly progressive neurological deficits, limb weakness, sensory loss, and pain. Diagnosing drop metastasis is challenging and MRI with gadolinium remains the gold standard modality for investigation. Surgical resection followed by radiotherapy remains the primary treatment option, whereas chemotherapy serves a palliative role in cases of recurrence or disseminated metastases.

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脊髓室管膜瘤的髓内转移。

下落转移或髓内脊髓转移（ISCM）是一种罕见的疾病，占中枢神经系统或脊髓转移的0.9%-5%。它起源于肿瘤细胞通过脑脊液（CSF）扩散，通常影响胸椎和腰椎。临床特征包括快速进行性神经功能缺损、肢体无力、感觉丧失和疼痛。诊断滴转移是具有挑战性的，MRI加钆仍然是研究的金标准模式。手术切除后放疗仍然是主要的治疗选择，而化疗在复发或播散性转移的情况下起到缓和作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Pakistan Medical Association Medicine-General Medicine

CiteScore

1.10

自引率

11.10%

发文量

983

审稿时长

3-6 weeks

期刊介绍： Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.