Demographic and regional mortality trends in dilated cardiomyopathy in the United States; 1999-2020.

IF 2.3 Q2 MEDICINE, GENERAL & INTERNAL
SAGE Open Medicine Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI:10.1177/20503121251329806
Syed Sarmad Javaid, Syed Usama Ashraf, Anoud Khan, Muntaha Irfan, Muhammad Usman Alamgir, Syed Daniyal Ahmed Jilanee, Hamiz Faisal, Muhammad Salman Peryani, Noor Ul Ain, Ismail Khan
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Abstract

Background: Dilated cardiomyopathy significantly impacts mortality and hospitalizations in the U.S., yet trends in dilated cardiomyopathy-related mortality are underreported. This retrospective study examines the trends in dilated cardiomyopathy-related mortality between 1999 and 2020.

Methods: The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was analyzed to study the trends in dilated cardiomyopathy-related mortality. Age-adjusted mortality rates per 100,000 people and annual percent changes with 95% CIs were determined. Joinpoint regression analysis was used to assess the trends in the overall demographic, geographic, and place-of-death variables.

Results: There were 168,702 dilated cardiomyopathy-related deaths reported between 1999 and 2020. The age-adjusted mortality rate declined from 3.40 in 1999 to 1.71 in 2020. Men unfailingly had a higher age-adjusted mortality rate than women. Non-Hispanic Black or African Americans had the highest age-adjusted mortality rate compared to other races, with a recent increase in annual percent change from 2015 to 2020. Hispanics, or Latinos, also showed an alarming rise in annual percent change of 11.10 from 2018 to 2020. Significant geographical variations were noted, with states in the top 90th percentile (Michigan, Washington, and Delaware) having approximately three times the age-adjusted mortality rate compared to states that fell in the lower 10th percentile.

Conclusion: Despite overall declines, racial and regional disparities persist, owing to the growing clinical burden. Targeted research and interventions are key to addressing disparities and reducing dilated cardiomyopathy-related mortality.

美国扩张型心肌病的人口统计学和地区死亡率趋势1999 - 2020。
背景:在美国,扩张型心肌病显著影响死亡率和住院率,但扩张型心肌病相关死亡率的趋势被低估。本回顾性研究调查了1999年至2020年间扩张型心肌病相关死亡率的趋势。方法:分析美国疾病控制与预防中心广泛的流行病学研究在线数据数据库,研究扩张型心肌病相关死亡率的趋势。确定了每10万人的年龄调整死亡率和95% ci的年百分比变化。采用联结点回归分析来评估总体人口学、地理和死亡地点变量的趋势。结果:1999年至2020年间,有168,702例扩张型心肌病相关死亡报告。年龄调整死亡率从1999年的3.40下降到2020年的1.71。男性的年龄调整死亡率始终高于女性。与其他种族相比,非西班牙裔黑人或非洲裔美国人的年龄调整死亡率最高,最近从2015年到2020年的年增长率有所上升。从2018年到2020年,拉美裔美国人的年增长率也惊人地上升了11.10%。注意到显著的地理差异,排名前90百分位的州(密歇根州、华盛顿州和特拉华州)的年龄调整死亡率大约是排名后10百分位的州的三倍。结论:尽管总体下降,但由于临床负担的增加,种族和地区差异仍然存在。有针对性的研究和干预是解决差异和降低扩张型心肌病相关死亡率的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
SAGE Open Medicine
SAGE Open Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.50
自引率
4.30%
发文量
289
审稿时长
12 weeks
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