Risk Factors for Suicidal Ideation and Attempt in Patients With Skull Base Tumors.

IF 2.6 3区医学 Q1 OTORHINOLARYNGOLOGY

Otolaryngology- Head and Neck Surgery Pub Date : 2025-04-01 Epub Date: 2025-01-07 DOI:10.1002/ohn.1124

Tony Chung, Shaun Edalati, Vikram Vasan, Alfred Marc Iloreta, Satish Govindaraj

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引用次数: 0

Abstract

Objective: Patients with head and neck cancer experience suicide rates significantly higher than the general population. However, the relationship between skull base tumors (SBTs) and suicidal ideation and attempt (SIA) remains underexplored. This study aims to identify sociodemographic and clinical risk factors for SIA among patients with SBTs.

Methods: A retrospective cohort study was conducted using the National Inpatient Sample (2016-2019) to analyze 275,195 hospitalizations involving SBTs. Survey-weighted methods were used to assess univariable and multivariable risk factors for SIA.

Results: Among SBT patients, 2160 (0.78%) were diagnosed with SIA. Younger age (adjusted odds ratio [aOR]: 0.98; P < .001) and emergent admissions (aOR: 2.25; P < .001) were strongly associated with SIA. Socioeconomic difficulties were one of the most significant predictors (aOR: 7.57; P < .001). Depressive, bipolar, and adjustment disorders were the strongest mental health comorbidity predictors (aOR: 8.18, 7.24, 5.19, respectively; P < .001). Alcohol and cannabis use disorders also elevated SIA risk (aOR: 2.79, 2.29, respectively; P < .001). Protective factors included treatment in Western hospitals (aOR: 0.52; P < .001) and undergoing surgery (aOR: 0.29-0.36; P < .001). Meningiomas were associated with lower SIA odds (aOR: 0.68; P = .013), while pituitary adenomas showed a significant association in univariable analysis.

Conclusion: Younger age, socioeconomic difficulties, mental health comorbidities, and substance use are key risk factors for SIA in SBT patients, while surgery and treatment in Western hospitals are protective. Regular suicidality screening and proactive mental health interventions are essential for improving outcomes in this vulnerable population.

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来源期刊

Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

6.70

自引率

2.90%

发文量

250

审稿时长

2-4 weeks

期刊介绍： Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.