{"title":"Transforming Drug Discovery with Miniaturized Predictive Tissue Models.","authors":"Mohsen Akbari","doi":"10.3390/mi16030299","DOIUrl":null,"url":null,"abstract":"<p><p>Drug development is a lengthy and expensive process that involves screening thousands of potential candidates in vitro, followed by pre-clinical efficacy, pharmacokinetic, and pharmacodynamic studies in relevant animal models, before evaluating the safety and efficacy of a drug in clinical trials [...].</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 3","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11944397/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Micromachines","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/mi16030299","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Drug development is a lengthy and expensive process that involves screening thousands of potential candidates in vitro, followed by pre-clinical efficacy, pharmacokinetic, and pharmacodynamic studies in relevant animal models, before evaluating the safety and efficacy of a drug in clinical trials [...].
期刊介绍:
Micromachines (ISSN 2072-666X) is an international, peer-reviewed open access journal which provides an advanced forum for studies related to micro-scaled machines and micromachinery. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.