Aiying Yu, Lingli Sun, Lian Chen, Dan Wang, Zhiyi Li, Yuan Wang, Zhenjiang Wang, Sen Lin
{"title":"The biological functions of proanthocyanidin and its application in pig production.","authors":"Aiying Yu, Lingli Sun, Lian Chen, Dan Wang, Zhiyi Li, Yuan Wang, Zhenjiang Wang, Sen Lin","doi":"10.3389/fvets.2025.1565501","DOIUrl":null,"url":null,"abstract":"<p><p>Proanthocyanidins (PACs) are natural polyphenolic compounds widely distributed in various plants, which are mixtures of oligomers and polymers formed by the polymerization of different numbers of catechins and epicatechins. PACs exhibit a range of biological activities, including antioxidant, anti-inflammatory, anti-cancer, anti-atherosclerotic, hypoglycemic, and antihypertensive effects, as well as the ability to regulate intestinal flora and promote fat metabolism. These properties render PACs highly promising for applications in the food, pharmaceutical, and cosmetic industries, garnering substantial interest from researchers globally. Additionally, PACs demonstrate significant nutritional benefits in animal husbandry. Dietary PACs can enhance animal growth, mitigate oxidative stress, decrease feeding expenses, and offer an environmentally friendly, antibiotic-free alternative. Therefore, PACs have great application potential in the field of pig production. This article reviews the basic properties, biological functions, and research status and application in pig production of PACs, aiming to provide theoretical guidance for the development of substitute antibiotic feed additives.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1565501"},"PeriodicalIF":2.6000,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938249/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Veterinary Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fvets.2025.1565501","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Proanthocyanidins (PACs) are natural polyphenolic compounds widely distributed in various plants, which are mixtures of oligomers and polymers formed by the polymerization of different numbers of catechins and epicatechins. PACs exhibit a range of biological activities, including antioxidant, anti-inflammatory, anti-cancer, anti-atherosclerotic, hypoglycemic, and antihypertensive effects, as well as the ability to regulate intestinal flora and promote fat metabolism. These properties render PACs highly promising for applications in the food, pharmaceutical, and cosmetic industries, garnering substantial interest from researchers globally. Additionally, PACs demonstrate significant nutritional benefits in animal husbandry. Dietary PACs can enhance animal growth, mitigate oxidative stress, decrease feeding expenses, and offer an environmentally friendly, antibiotic-free alternative. Therefore, PACs have great application potential in the field of pig production. This article reviews the basic properties, biological functions, and research status and application in pig production of PACs, aiming to provide theoretical guidance for the development of substitute antibiotic feed additives.
期刊介绍:
Frontiers in Veterinary Science is a global, peer-reviewed, Open Access journal that bridges animal and human health, brings a comparative approach to medical and surgical challenges, and advances innovative biotechnology and therapy.
Veterinary research today is interdisciplinary, collaborative, and socially relevant, transforming how we understand and investigate animal health and disease. Fundamental research in emerging infectious diseases, predictive genomics, stem cell therapy, and translational modelling is grounded within the integrative social context of public and environmental health, wildlife conservation, novel biomarkers, societal well-being, and cutting-edge clinical practice and specialization. Frontiers in Veterinary Science brings a 21st-century approach—networked, collaborative, and Open Access—to communicate this progress and innovation to both the specialist and to the wider audience of readers in the field.
Frontiers in Veterinary Science publishes articles on outstanding discoveries across a wide spectrum of translational, foundational, and clinical research. The journal''s mission is to bring all relevant veterinary sciences together on a single platform with the goal of improving animal and human health.