Olalekan Akinbo, Bongani Nkhabindze, Josephine Amedu, Rufus Ebegba, Agnes Asagbra, Billy Omboki Ratemo, Susan Angira Dada, Anne Muia, Roy Mugiira, Lilian Chimphepo, Leeford Oko Wristberg, Mathurin W Rouamba, Koussao Some, Valter N A Nuaila, Alsácia Atanásio, Olufunke Bolatito Shittu, Charles Oluwaseun Adetunji, Loubna Hamidi, Elinasi Monga, Silas Obukosia, Muyiwa Seyi Adegbaju, Samuel Acheampong, Estherine Fotabong
{"title":"Africa and zero hunger agenda: genome editing policy landscape, challenges and opportunities.","authors":"Olalekan Akinbo, Bongani Nkhabindze, Josephine Amedu, Rufus Ebegba, Agnes Asagbra, Billy Omboki Ratemo, Susan Angira Dada, Anne Muia, Roy Mugiira, Lilian Chimphepo, Leeford Oko Wristberg, Mathurin W Rouamba, Koussao Some, Valter N A Nuaila, Alsácia Atanásio, Olufunke Bolatito Shittu, Charles Oluwaseun Adetunji, Loubna Hamidi, Elinasi Monga, Silas Obukosia, Muyiwa Seyi Adegbaju, Samuel Acheampong, Estherine Fotabong","doi":"10.3389/fbioe.2025.1526851","DOIUrl":null,"url":null,"abstract":"<p><p>Africa has historically struggled to adopt innovative agricultural technologies, which has significantly hindered efforts to ensure food security and improve livelihoods over the past century. A major obstacle in this regard has been the persistent skepticism surrounding the potential benefits of agricultural biotechnology. The challenges contributing to this skepticism include a notable knowledge gap among stakeholders, widespread technophobia, or fear of technology, as well as inconsistencies with global agreements such as the Convention on Biological Diversity (CBB). Although these challenges are not exclusive to Africa, they disproportionately impact the continent, making the need for effective solutions even more urgent. This paper investigates the national government policy landscape in five African countries that are poised to create a regulatory environment conducive to deploying genome editing technology for improved agricultural productivity. This exploration aligns with the continental agricultural policy initiatives, notably the \"CAADP Malabo Declaration\" and the soon-to-be-signed \"CAADP Kampala Declaration.\" Aligning with the African Union's continental agenda on agricultural transformation, as outlined in the Malabo Declaration and other key documents, is crucial for adopting innovative agricultural technologies like genome editing. Such alignment becomes increasingly critical for realizing the objectives set forth in the post-Malabo Declaration, with the Kampala Declaration playing a vital role in its implementation. This cohesive approach will not only foster agricultural innovation but also expedite development across the continent, addressing the pressing needs of food security and livelihoods in Africa.</p>","PeriodicalId":12444,"journal":{"name":"Frontiers in Bioengineering and Biotechnology","volume":"13 ","pages":"1526851"},"PeriodicalIF":4.3000,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936932/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Bioengineering and Biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3389/fbioe.2025.1526851","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Africa has historically struggled to adopt innovative agricultural technologies, which has significantly hindered efforts to ensure food security and improve livelihoods over the past century. A major obstacle in this regard has been the persistent skepticism surrounding the potential benefits of agricultural biotechnology. The challenges contributing to this skepticism include a notable knowledge gap among stakeholders, widespread technophobia, or fear of technology, as well as inconsistencies with global agreements such as the Convention on Biological Diversity (CBB). Although these challenges are not exclusive to Africa, they disproportionately impact the continent, making the need for effective solutions even more urgent. This paper investigates the national government policy landscape in five African countries that are poised to create a regulatory environment conducive to deploying genome editing technology for improved agricultural productivity. This exploration aligns with the continental agricultural policy initiatives, notably the "CAADP Malabo Declaration" and the soon-to-be-signed "CAADP Kampala Declaration." Aligning with the African Union's continental agenda on agricultural transformation, as outlined in the Malabo Declaration and other key documents, is crucial for adopting innovative agricultural technologies like genome editing. Such alignment becomes increasingly critical for realizing the objectives set forth in the post-Malabo Declaration, with the Kampala Declaration playing a vital role in its implementation. This cohesive approach will not only foster agricultural innovation but also expedite development across the continent, addressing the pressing needs of food security and livelihoods in Africa.
期刊介绍:
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs.
In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.