Palladium-Catalyzed Carbonylative Sonogashira Transformations: Advancements and Insights

IF 7.5 2区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Prasanth Vishnu, Padinjare Veetil Saranya, Prof. Dr. Gopinathan Anilkumar
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引用次数: 0

Abstract

Palladium-catalyzed carbonylative reactions, used as a tool for the insertion of carbonyl group into organic moieties, is a synthetically useful transformation. Carbonylative Sonogashira coupling is a convenient approach for the synthesis of α,β-acetylenic ketones which are important class of molecules in pharmaceutical and industrial fields. Development of greener approaches and environmentally benign catalytic systems put forward enormous opportunities in this field and moreover, these researches indicate the formation of heterocycles via this carbonylation strategy, which is a major highlight. Herein, we discuss the progress achieved in palladium-catalyzed carbonylative Sonogashira coupling from 2013 to 2024 and its future prospects.

Abstract Image

钯催化羰基化Sonogashira转化:进展和见解。
钯催化羰基化反应是一种合成上有用的转化,是将羰基插入有机基团的一种工具。羰基Sonogashira偶联是合成α,β-乙基酮类分子的一种简便方法,是医药和工业领域的重要分子。绿色途径和环境友好型催化体系的发展为该领域提供了巨大的机遇,并且这些研究表明,通过这种羰基化策略形成杂环是该领域的一大亮点。本文讨论了2013 - 2024年钯催化羰基Sonogashira偶联的研究进展及未来展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chemical record
Chemical record 化学-化学综合
CiteScore
11.00
自引率
3.00%
发文量
188
审稿时长
>12 weeks
期刊介绍: The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.
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