Treatment of Port-Wine Birthmarks Using a Large-Spot, Variable Sequenced, Long-Pulsed KTP-Laser—A Retrospective Analysis

IF 2.3 4区医学 Q2 DERMATOLOGY

Journal of Cosmetic Dermatology Pub Date : 2025-03-28 DOI:10.1111/jocd.70152

Lynhda Nguyen, Stefan W. Schneider, Katharina Herberger

{"title":"Treatment of Port-Wine Birthmarks Using a Large-Spot, Variable Sequenced, Long-Pulsed KTP-Laser—A Retrospective Analysis","authors":"Lynhda Nguyen, Stefan W. Schneider, Katharina Herberger","doi":"10.1111/jocd.70152","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Pulsed-dye lasers (PDLs) are currently regarded as the gold standard for treating port-wine birthmarks (PWBs). Recently, the large-spot, variable-sequenced, long-pulsed potassium titanyl phosphate laser (KTP) has been introduced as a promising alternative for addressing dermatologic vascular lesions. Despite its growing use, data on the efficacy and safety of this technology in treating PWBs over an extended period remain limited.</p>\n </section>\n \n <section>\n \n <h3> Aims</h3>\n \n <p>To evaluate the efficacy and safety of a large-spot, variable-sequenced, long-pulsed KTP in the treatment of PWBs over 3 years.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A retrospective analysis was conducted on PWB patients treated with the KTP between October 2021 and October 2024. Treatment outcomes were assessed using colorimetric analysis based on the CIE L*a*b* color space system and by measuring the surface area of the lesions. All adverse events (AEs) were documented.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A total of 69 patients were included, with a mean age of 36.5 ± 15.6 years. 59.4% were female. Colorimetric analysis revealed an average lightening of PWBs by 75.7% ± 36.1%. Additionally, the surface area of the lesions decreased by 25.3% ± 24.4%. No severe AEs, such as post-inflammatory hyperpigmentation or scarring, were observed.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>This study highlights the potential of large-spot, variable-pulsed KTP as a safe and effective alternative for treating PWBs, demonstrating significant lesion lightening and surface area reduction. With no severe AEs observed, the findings suggest that this technology could complement or serve as an alternative to PDLs. Further prospective studies are warranted to optimize treatment protocols and evaluate long-term outcomes compared to PDL and other vascular treatment options.</p>\n </section>\n </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70152","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cosmetic Dermatology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70152","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Pulsed-dye lasers (PDLs) are currently regarded as the gold standard for treating port-wine birthmarks (PWBs). Recently, the large-spot, variable-sequenced, long-pulsed potassium titanyl phosphate laser (KTP) has been introduced as a promising alternative for addressing dermatologic vascular lesions. Despite its growing use, data on the efficacy and safety of this technology in treating PWBs over an extended period remain limited.

Aims

To evaluate the efficacy and safety of a large-spot, variable-sequenced, long-pulsed KTP in the treatment of PWBs over 3 years.

Methods

A retrospective analysis was conducted on PWB patients treated with the KTP between October 2021 and October 2024. Treatment outcomes were assessed using colorimetric analysis based on the CIE L*a*b* color space system and by measuring the surface area of the lesions. All adverse events (AEs) were documented.

Results

A total of 69 patients were included, with a mean age of 36.5 ± 15.6 years. 59.4% were female. Colorimetric analysis revealed an average lightening of PWBs by 75.7% ± 36.1%. Additionally, the surface area of the lesions decreased by 25.3% ± 24.4%. No severe AEs, such as post-inflammatory hyperpigmentation or scarring, were observed.

Conclusion

This study highlights the potential of large-spot, variable-pulsed KTP as a safe and effective alternative for treating PWBs, demonstrating significant lesion lightening and surface area reduction. With no severe AEs observed, the findings suggest that this technology could complement or serve as an alternative to PDLs. Further prospective studies are warranted to optimize treatment protocols and evaluate long-term outcomes compared to PDL and other vascular treatment options.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Cosmetic Dermatology DERMATOLOGY-

CiteScore

4.30

自引率

13.00%

发文量

818

审稿时长

>12 weeks

期刊介绍： The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.