{"title":"Enteropathogenic Escherichia coli (EPEC) Causes Chronic Diarrhea and Hyponatremia in an Adult","authors":"Saisai Chen, Colin Feuille","doi":"10.1002/ccr3.70288","DOIUrl":null,"url":null,"abstract":"<p>Enteropathogenic <i>Escherichia coli</i> (EPEC) is frequently identified on gastrointestinal pathogen multiplex polymerase chain reaction testing. However, it is unclear whether EPEC causes diarrhea in adults. We describe the case of a 48-year-old man living in the United States who presented with 6 weeks of large-volume watery diarrhea and significant hyponatremia refractory to hypertonic saline and fluid restriction, who was found to have EPEC. Ciprofloxacin was initiated, resulting in the resolution of both diarrhea and hyponatremia. This case demonstrates that EPEC can be pathogenic in adults and can be associated with significant hyponatremia.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70288","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70288","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Enteropathogenic Escherichia coli (EPEC) is frequently identified on gastrointestinal pathogen multiplex polymerase chain reaction testing. However, it is unclear whether EPEC causes diarrhea in adults. We describe the case of a 48-year-old man living in the United States who presented with 6 weeks of large-volume watery diarrhea and significant hyponatremia refractory to hypertonic saline and fluid restriction, who was found to have EPEC. Ciprofloxacin was initiated, resulting in the resolution of both diarrhea and hyponatremia. This case demonstrates that EPEC can be pathogenic in adults and can be associated with significant hyponatremia.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).