Recent applications and advancement of conductive hydrogels in biosensing, bioelectronics and bioengineering

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-03-27 DOI:10.1007/s00604-025-07123-y

Shi-Yu Chen, Tao Feng, Zeng-Qiang Wu, Ning Bao

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Abstract

Conductive hydrogels (CHs) are characterized by their distinctive three-dimensional (3D) network architecture enhanced by physically entangled or chemically cross-linked polymer chains. In recent years, these materials have garnered significant scientific interest owing to their unique combination of inherent electrical conductivity and remarkable capability to transduce external stimuli into measurable electronic signals. The immense potentials of those CHs in a number of applications catalyzed this review to summarize their specific properties and applications in biosensing, bioelectronics and bioengineering. Firstly, the preparation and unique properties of CHs were summarized, including mechanical properties, adhesion properties, self-healing capabilities, conductivity, biodegradability, and biocompatibility. We demonstrated tremendous potentials of CHs in the real world by showcasing their broad applications in biosensing (such as nerve sensing, strain sensing, glucose sensing, tumor sensing, temperature sensing, and environmental sensing), bioelectronics and bioengineering (such as treatment of cardiac and wound healing). Finally, by presenting current challenges and issues of CHs, future potential research directions were outlined for their applications in the study of biosensing, bioelectronics and bioengineering.

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.