Walther Parson , Amelie Alterauge , Christina Amory , Sarah Heinze , Stefan Hölzl , Ralf G. Jahn , Christine Lehn , Timo Sänger , Catarina Xavier , Andreas Tillmar , Karen Nolte , Sabine Lutz-Bonengel , Sara Doll
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引用次数: 0
Abstract
Two mounted skeletons assigned to the famous German criminals Schinderhannes and Hölzerlips were on display at the Anatomical Collection of Heidelberg University for two centuries. However, doubts about their authenticity existed for decades. Based on historical research, an interdisciplinary team with experts from the fields of anatomy, radiology, anthropology, genealogy and molecular biology set out to examine the remains from the following perspectives: (1) Isotope analyses were carried out to compare inferred childhood residences with historical narratives, (2) anthropological and radiological examinations were documented and compared with historical records, (3) genealogical research identified a living male descendant along the maternal line and (4) mitogenome sequencing as well as nuclear SNP analysis using the FORCE panel provided compelling evidence for the identification of Schinderhannes’ remains. Additionally, the prediction of eye, hair and skin color from the DNA offered science-based data to clarify conflicting historical records.
期刊介绍:
Forensic Science International: Genetics is the premier journal in the field of Forensic Genetics. This branch of Forensic Science can be defined as the application of genetics to human and non-human material (in the sense of a science with the purpose of studying inherited characteristics for the analysis of inter- and intra-specific variations in populations) for the resolution of legal conflicts.
The scope of the journal includes:
Forensic applications of human polymorphism.
Testing of paternity and other family relationships, immigration cases, typing of biological stains and tissues from criminal casework, identification of human remains by DNA testing methodologies.
Description of human polymorphisms of forensic interest, with special interest in DNA polymorphisms.
Autosomal DNA polymorphisms, mini- and microsatellites (or short tandem repeats, STRs), single nucleotide polymorphisms (SNPs), X and Y chromosome polymorphisms, mtDNA polymorphisms, and any other type of DNA variation with potential forensic applications.
Non-human DNA polymorphisms for crime scene investigation.
Population genetics of human polymorphisms of forensic interest.
Population data, especially from DNA polymorphisms of interest for the solution of forensic problems.
DNA typing methodologies and strategies.
Biostatistical methods in forensic genetics.
Evaluation of DNA evidence in forensic problems (such as paternity or immigration cases, criminal casework, identification), classical and new statistical approaches.
Standards in forensic genetics.
Recommendations of regulatory bodies concerning methods, markers, interpretation or strategies or proposals for procedural or technical standards.
Quality control.
Quality control and quality assurance strategies, proficiency testing for DNA typing methodologies.
Criminal DNA databases.
Technical, legal and statistical issues.
General ethical and legal issues related to forensic genetics.