Diagnosis of donor-derived Malassezia restricta & Aspergillus species invasive fungal infection in renal transplant recipient using next generation sequencing – A report of 2 cases and literature review

IF 4.7 3区医学 Q1 INFECTIOUS DISEASES

Journal of Infection and Public Health Pub Date : 2025-03-12 DOI:10.1016/j.jiph.2025.102742

Reem M. Alameer , Hamsa Tayeb , Amna Magrashi , Abdulmohsan Alqasabi , Ahmed Nazmi , Amani Yamani , Reem S. Almaghrabi

引用次数: 0

Abstract

Diagnosing donor-derived fungal infection in solid organ transplant recipients can be particularly challenging and is associated with high mortality. Here, we report two cases of Malassezia restricta and Aspergillus spp donor-derived fungal infection in renal transplant recipients leading to graft loss. Fortunately, both patients achieved full recovery with the administration of antifungal therapy.

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下一代测序诊断肾移植受者供体限制性马拉色菌及曲霉菌侵袭性真菌感染2例报告并文献复习

在实体器官移植受者中诊断供体来源的真菌感染可能特别具有挑战性，并且与高死亡率相关。在这里，我们报告两例限制马拉色菌和曲霉属供体来源的真菌感染在肾移植受者导致移植损失。幸运的是，两名患者在接受抗真菌治疗后均完全康复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

13.10

自引率

1.50%

发文量

203

审稿时长

96 days

期刊介绍： The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.