A Novel Bulk Planar Junctionless Field-Effect Transistor for High-Performance Biosensing.

IF 4.9 3区 工程技术 Q1 CHEMISTRY, ANALYTICAL
Jeongmin Son, Chan Heo, Hyeongyu Kim, M Meyyappan, Kihyun Kim
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Abstract

Biologically sensitive field-effect transistors (BioFETs) have advanced the biosensing capabilities in various fields such as healthcare, security and environmental monitoring. Here, we propose a junctionless BioFET (JL-BioFET) for the high-sensitivity and low-cost detection of biomolecules and analyze it using detailed device simulations. In contrast to the conventional FET with junctions, the JL-BioFET simplifies fabrication by doping the source, channel and drain simultaneously with the same types of impurities, thereby reducing the fabrication effort and cost. Additionally, if the device is designed with optimal bias, it can operate with only the source and drain terminals, which reduces power consumption. Thus, cost reduction and reduced power consumption are strong motivations to pursue a new design. Therefore, we simulated two JL-BioFET structures (SOI JL, bulk JL) that operate without a gate electrode and compared their biosensing performances. The bulk JL-BioFET showed an average sensitivity three times higher than that of the SOI JL-BioFET across varying charge levels. Then, we optimized the sensing performance of the bulk JL-BioFET by adjusting three key parameters: the active layer thickness and the doping concentrations of the active layer and substrate. These encouraging results are expected to lead to future fabrication efforts to realize bulk JL-BioFETs for high-performance biosensing.

一种用于高性能生物传感的新型体平面无结场效应晶体管。
生物敏感场效应晶体管(biofet)在医疗保健、安全和环境监测等各个领域具有先进的生物传感能力。在这里,我们提出了一种无结生物ofet (JL-BioFET),用于高灵敏度和低成本的生物分子检测,并使用详细的设备模拟对其进行分析。与传统的带结FET相比,JL-BioFET通过同时掺杂相同类型的杂质来简化源、通道和漏极的制造,从而减少了制造工作量和成本。此外,如果器件设计为最佳偏置,则可以仅使用源极和漏极工作,从而降低功耗。因此,降低成本和降低功耗是追求新设计的强烈动机。因此,我们模拟了两种JL- biofet结构(SOI JL, bulk JL)在没有栅极的情况下工作,并比较了它们的生物传感性能。在不同的电荷水平下,散装JL-BioFET的平均灵敏度比SOI JL-BioFET高3倍。然后,我们通过调整三个关键参数:有源层厚度和有源层和衬底的掺杂浓度来优化大块JL-BioFET的传感性能。这些令人鼓舞的结果有望导致未来的制造努力,以实现高性能生物传感的批量jl - biofet。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biosensors-Basel
Biosensors-Basel Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.60
自引率
14.80%
发文量
983
审稿时长
11 weeks
期刊介绍: Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.
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