Risk of bleeding and predictors of hemorrhagic transformation in patients with stroke after thrombolysis.

Q3 Nursing

Revista gaucha de enfermagem / EENFUFRGS Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI:10.1590/1983-1447.2025.20240086.en

Daniela Barella, Karina de Oliveira Azzolin, Michelle Dornelles Santarém, Ruy de Almeida Barcellos, Luísa Brehm Santana

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引用次数: 0

Abstract

Objective: To analyze the prediction of hemorrhagic transformation in patients with ischemic stroke undergoing thrombolytic therapy and its association with the nursing diagnosis "Risk of bleeding".

Method: Retrospective cohort study in patients with post-thrombolysis ischemic stroke from a hospital in Rio Grande do Sul from January 2019 to December 2021. The patient data were extrected from electronic medical records. After processing, univariable and multivariable analysis was conducted using Poisson regression with robust variance.

Results: 249 patients were analyzed, 43 (17.4%) had hemorrhagic transformation, hospitalization time was 8 (5-12.5) days and 25 (10%) died. The predictors of hemorrhagic transformation were: increased age, pre-thrombolysis National Institute of Health Stroke Scale score and use of oxygen therapy via nasal goggles and Hudson mask. The nursing diagnosis "Risk of bleeding" was not associated with hemorrhagic transformation.

Conclusion: The predictors found can improve the nursing diagnosis "Risk of bleeding", but there was no correlation observed between this and the occurrence of hemorrhagic transformation.

查看原文本刊更多论文

脑卒中患者溶栓后出血风险及出血转化的预测因素。

目的：分析缺血性脑卒中溶栓治疗患者出血转化的预测及其与护理诊断“出血风险”的关系。方法：回顾性队列研究2019年1月至2021年12月南大德州某医院溶栓后缺血性脑卒中患者。患者数据是从电子病历中提取的。处理后，采用稳健方差的泊松回归进行单变量和多变量分析。结果：249例患者中43例（17.4%）发生出血转化，住院时间8 (5 ~ 12.5)d，死亡25例（10%）。出血转化的预测因素为：年龄增加、溶栓前美国国立卫生研究院卒中量表评分和通过鼻镜和Hudson面罩进行氧疗。护理诊断“出血风险”与出血转化无关。结论：发现的预测因子可提高护理诊断“出血风险”，但与出血转化的发生无相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista gaucha de enfermagem / EENFUFRGS Medicine-Medicine (all)

CiteScore

1.70

自引率

0.00%

发文量

118

审稿时长

16 weeks

期刊介绍： A Escola de Enfermagem da Universidade Federal do Rio Grande do Sul edita e publica a Revista Gaúcha de Enfermagem para divulgar a produção científica da Enfermagem e áreas afins. Foi criada em 1976 e atualmente tem periodicidade trimestral.