Samo Daniel, Ana Paula D Moraes, Irene K Meki, Tirumala B K Settypalli, Charles E Lamien, Gottlieb Aikukutu, Siegfried Khaiseb, William G Dundon, Juliet Kabajani
{"title":"Characterization of African swine fever virus in Angola, 2024.","authors":"Samo Daniel, Ana Paula D Moraes, Irene K Meki, Tirumala B K Settypalli, Charles E Lamien, Gottlieb Aikukutu, Siegfried Khaiseb, William G Dundon, Juliet Kabajani","doi":"10.1007/s11259-025-10721-z","DOIUrl":null,"url":null,"abstract":"<p><p>In February 2024, an outbreak of African Swine Fever (ASF) was reported in a commercial pig farm in southwestern Angola. Five clinical samples were collected and sent to the Central Veterinary Laboratory in Windhoek, Namibia and the presence of ASF virus (ASFV) was confirmed. Sequencing of the C-terminus of the B646L gene (p72 protein), the complete E183L gene (p54 protein), the central hypervariable region (CVR) of the B602L gene, and the partial CD2v gene (used for serotyping) was performed on DNA isolated from the samples. Phylogenetic analyses of the B646L (p72) and the E183L gene (p54) revealed that the samples were identical to each other and belonged to genotype I. The viruses belonged to serotype 2 and had CVR profiles similar to those commonly found in ASFVs of genotype I. This is the first detailed report of ASFV in Angola and will be of interest to regional veterinary authorities.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 3","pages":"154"},"PeriodicalIF":1.8000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Research Communications","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1007/s11259-025-10721-z","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
In February 2024, an outbreak of African Swine Fever (ASF) was reported in a commercial pig farm in southwestern Angola. Five clinical samples were collected and sent to the Central Veterinary Laboratory in Windhoek, Namibia and the presence of ASF virus (ASFV) was confirmed. Sequencing of the C-terminus of the B646L gene (p72 protein), the complete E183L gene (p54 protein), the central hypervariable region (CVR) of the B602L gene, and the partial CD2v gene (used for serotyping) was performed on DNA isolated from the samples. Phylogenetic analyses of the B646L (p72) and the E183L gene (p54) revealed that the samples were identical to each other and belonged to genotype I. The viruses belonged to serotype 2 and had CVR profiles similar to those commonly found in ASFVs of genotype I. This is the first detailed report of ASFV in Angola and will be of interest to regional veterinary authorities.
期刊介绍：
Veterinary Research Communications publishes fully refereed research articles and topical reviews on all aspects of the veterinary sciences. Interdisciplinary articles are particularly encouraged, as are well argued reviews, even if they are somewhat controversial.
The journal is an appropriate medium in which to publish new methods, newly described diseases and new pathological findings, as these are applied to animals. The material should be of international rather than local interest. As it deliberately seeks a wide coverage, Veterinary Research Communications provides its readers with a means of keeping abreast of current developments in the entire field of veterinary science.
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