Gut Mycobiome Changes During COVID-19 Disease.

IF 4.2 2区生物学 Q2 MICROBIOLOGY

Journal of Fungi Pub Date : 2025-03-03 DOI:10.3390/jof11030194

Danil V Krivonos, Dmitry E Fedorov, Ksenia M Klimina, Vladimir A Veselovsky, Svetlana N Kovalchuk, Alexander V Pavlenko, Oleg O Yanushevich, Dmitry N Andreev, Filipp S Sokolov, Aleksey K Fomenko, Mikhail K Devkota, Nikolai G Andreev, Andrey V Zaborovsky, Sergei V Tsaregorodtsev, Vladimir V Evdokimov, Natella I Krikheli, Petr A Bely, Oleg V Levchenko, Igor V Maev, Vadim M Govorun, Elena N Ilina

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引用次数: 0

Abstract

The majority of metagenomic studies are based on the study of bacterial biota. At the same time, the COVID-19 pandemic has prompted interest in the study of both individual fungal pathogens and fungal communities (i.e., the mycobiome) as a whole. Here, in this work, we investigated the human gut mycobiome during COVID-19. Stool samples were collected from patients at two time points: at the time of admission to the hospital (the first time point) and at the time of discharge from the hospital (the second time point). The results of this study revealed that Geotrichum sp. is more represented in a group of patients with COVID-19. Therefore, Geotrichum sp. is elevated in patients at the time of admission to the hospital and underestimated at the time of discharge. Additionally, the influence of factors associated with the diversity of fungal gut microbiota was separately studied, including disease severity and age factors.

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来源期刊

Journal of Fungi Medicine-Microbiology (medical)

CiteScore

6.70

自引率

14.90%

发文量

1151

审稿时长

11 weeks

期刊介绍： Journal of Fungi (ISSN 2309-608X) is an international, peer-reviewed scientific open access journal that provides an advanced forum for studies related to pathogenic fungi, fungal biology, and all other aspects of fungal research. The journal publishes reviews, regular research papers, and communications in quarterly issues. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on paper length. Full experimental details must be provided so that the results can be reproduced.