{"title":"Epithelial biology: Holding the corners together.","authors":"Tara M Finegan","doi":"10.1016/j.cub.2025.02.023","DOIUrl":null,"url":null,"abstract":"<p><p>A new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work reshapes our understanding of the mechanical regulation of epithelial permeability.</p>","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":"35 6","pages":"R232-R235"},"PeriodicalIF":8.1000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cub.2025.02.023","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
A new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work reshapes our understanding of the mechanical regulation of epithelial permeability.
期刊介绍:
Current Biology is a comprehensive journal that showcases original research in various disciplines of biology. It provides a platform for scientists to disseminate their groundbreaking findings and promotes interdisciplinary communication. The journal publishes articles of general interest, encompassing diverse fields of biology. Moreover, it offers accessible editorial pieces that are specifically designed to enlighten non-specialist readers.