{"title":"Cohesinopathies: Is enhancer disruption to blame?","authors":"Thomas M Guérin, Frank Uhlmann","doi":"10.1016/j.cub.2025.01.046","DOIUrl":null,"url":null,"abstract":"<p><p>Cohesinopathies are debilitating human developmental disorders. New research pins down mechanisms by which the chromosomal cohesin complex controls the intricate transcriptional program that underlies healthy human growth and development.</p>","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":"35 6","pages":"R214-R216"},"PeriodicalIF":8.1000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cub.2025.01.046","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Cohesinopathies are debilitating human developmental disorders. New research pins down mechanisms by which the chromosomal cohesin complex controls the intricate transcriptional program that underlies healthy human growth and development.
期刊介绍:
Current Biology is a comprehensive journal that showcases original research in various disciplines of biology. It provides a platform for scientists to disseminate their groundbreaking findings and promotes interdisciplinary communication. The journal publishes articles of general interest, encompassing diverse fields of biology. Moreover, it offers accessible editorial pieces that are specifically designed to enlighten non-specialist readers.