Noncontact optical 3D strain measurements in cervical soft tissues biomechanics by digital image correlation under tensile test: an experimental approach.
IF 4.3 3区 工程技术Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
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引用次数: 0
Abstract
Background: Digital image correlation (DIC) is widely used to measure surface strain in loaded objects. When studying the deformation of the cervical spine, the complexity and non-planarity of the structure complicate the speckle pattern required for applying DIC. While this non-invasive technique has shown promise in biomechanical testing, its application to cervical spine analysis presents unique challenges, particularly in achieving dynamic full-scale multi-aspect strain measurements. The aim of this paper is to introduce a method for exploring the stress-strain relationship on cervical cadaveric specimen by optical non-contact measurement system.
Method: Cervical cadaveric specimens were selected as subjects. Before testing, anatomical exposure, embedding, and spraying were performed sequentially. Specimen preparation was optimized through transverse process removal to enhance visualization of key anatomical structures. The surface strain under tensile testing was analyzed by the Aramis non-contact measurement system.
Result: High-quality three-dimensional strain images were obtained with improved inspection points across all aspects, particularly in the lateral aspect (5397.25 ± 723.76 vs. 3268.25 ± 573.17, P < 0.05). Under 60N tensile loading, strain distribution revealed concentration in soft tissue regions while preserving clear visualization of vertebral bodies, intervertebral discs, and foramina. Quantitative analysis shown consistent deformation patterns across cervical segments (C4-C7), with no significant differences in segmental parameters (P > 0.05).
Conclusion: The application of an optical non-contact measurement system in this study of cervical spine biomechanics has been proven effective. This method potentially mitigates some of the limitations associated with previous DIC techniques when applied to cervical cadaveric specimens. As a result, it enables more available measurements of multidimensional strain, which may enhance our understanding of the mechanics of the cervical spine.
期刊介绍：
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs.
In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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