PTSD in Patients Who Undergo Head and Neck Cancer Treatment: A Systematic Review.

IF 2.8 4区医学 Q2 ONCOLOGY

Current oncology Pub Date : 2025-02-26 DOI:10.3390/curroncol32030134

Orli Weiss, Juliana Runnels, Daniel R Dickstein, Kristin Hsieh, Lauren Jacobs, Anuja Shah, Danielle Arons, Samuel Reed, Kunal K Sindhu, Richard Bakst, Julie Bloom

{"title":"PTSD in Patients Who Undergo Head and Neck Cancer Treatment: A Systematic Review.","authors":"Orli Weiss, Juliana Runnels, Daniel R Dickstein, Kristin Hsieh, Lauren Jacobs, Anuja Shah, Danielle Arons, Samuel Reed, Kunal K Sindhu, Richard Bakst, Julie Bloom","doi":"10.3390/curroncol32030134","DOIUrl":null,"url":null,"abstract":"Background/objectives: Post-traumatic stress disorder (PTSD) can develop after exposure to real or perceived threats to life and is characterized by symptoms including intrusive thoughts, hyperarousal, and emotional numbness. While PTSD is well-studied in populations affected by disasters and combat, the impact of serious medical conditions like cancer and its treatments remain under-researched. Due to the aggressive nature of the disease, fear of recurrence, and disfiguring nature of treatments, patients with head and neck cancer (HNC) may experience a real or perceived risk of death. This systematic review synthesizes current knowledge on PTSD in patients with HNC.Methods: A systematic review was conducted per PRISMA guidelines. Five databases (PubMed, EMBASE, SCOPUS, CINAHL, and COCHRANE) were searched for studies describing PTSD in patients with and survivors of HNC. Studies with PTSD diagnosis and/or symptom data specific to patients with HNC were included.Results: Of 80 studies, 14 met the inclusion criteria. The most commonly used scale was the PTSD Checklist-Civilian Version. The prevalence of PTSD ranged from 8% to 41% across the studies. No significant differences were found with regards to PTSD prevalence by HNC tumor site, disease stage, or treatment modality. Two studies identified significant associations between PTSD after treatment and depression at the time of diagnosis. Patients with PTSD who received cognitive behavioral therapy showed improvement in their PTSD symptoms compared to those who did not.Conclusions: PTSD is common in individuals with HNC; however, the lack of a standardized approach to diagnosing PTSD in patients with and survivors of HNC creates challenges in identifying patients who may benefit from treatment. Given that HNC is the seventh most common cancer worldwide, with increasing incidence, there is a need to better understand the relationship between HNC and PTSD to allow for better PTSD screening, identification, and treatment to improve patients' health-related quality of life and provide optimal patient care.","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"32 3","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941172/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/curroncol32030134","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background/objectives: Post-traumatic stress disorder (PTSD) can develop after exposure to real or perceived threats to life and is characterized by symptoms including intrusive thoughts, hyperarousal, and emotional numbness. While PTSD is well-studied in populations affected by disasters and combat, the impact of serious medical conditions like cancer and its treatments remain under-researched. Due to the aggressive nature of the disease, fear of recurrence, and disfiguring nature of treatments, patients with head and neck cancer (HNC) may experience a real or perceived risk of death. This systematic review synthesizes current knowledge on PTSD in patients with HNC.

Methods: A systematic review was conducted per PRISMA guidelines. Five databases (PubMed, EMBASE, SCOPUS, CINAHL, and COCHRANE) were searched for studies describing PTSD in patients with and survivors of HNC. Studies with PTSD diagnosis and/or symptom data specific to patients with HNC were included.

Results: Of 80 studies, 14 met the inclusion criteria. The most commonly used scale was the PTSD Checklist-Civilian Version. The prevalence of PTSD ranged from 8% to 41% across the studies. No significant differences were found with regards to PTSD prevalence by HNC tumor site, disease stage, or treatment modality. Two studies identified significant associations between PTSD after treatment and depression at the time of diagnosis. Patients with PTSD who received cognitive behavioral therapy showed improvement in their PTSD symptoms compared to those who did not.

Conclusions: PTSD is common in individuals with HNC; however, the lack of a standardized approach to diagnosing PTSD in patients with and survivors of HNC creates challenges in identifying patients who may benefit from treatment. Given that HNC is the seventh most common cancer worldwide, with increasing incidence, there is a need to better understand the relationship between HNC and PTSD to allow for better PTSD screening, identification, and treatment to improve patients' health-related quality of life and provide optimal patient care.

查看原文本刊更多论文

头颈癌治疗患者的PTSD：一项系统综述。

背景/目的：创伤后应激障碍（PTSD）可在暴露于真实或感知的生命威胁后发展，其特征症状包括侵入性思想、过度觉醒和情绪麻木。虽然PTSD在受灾难和战争影响的人群中得到了很好的研究，但癌症等严重疾病的影响及其治疗方法仍未得到充分研究。由于疾病的侵袭性，对复发的恐惧以及治疗的毁容性，头颈癌（HNC）患者可能会经历真实或感知的死亡风险。本系统综述综合了目前关于HNC患者PTSD的知识。方法：根据PRISMA指南进行系统评价。检索了五个数据库（PubMed， EMBASE， SCOPUS， CINAHL和COCHRANE），以寻找描述HNC患者和幸存者PTSD的研究。研究纳入了HNC患者特有的PTSD诊断和/或症状数据。结果：80项研究中，14项符合纳入标准。最常用的量表是PTSD检查表-平民版。在这些研究中，PTSD的患病率从8%到41%不等。在HNC肿瘤部位、疾病分期或治疗方式方面，PTSD患病率无显著差异。两项研究确定了治疗后PTSD与诊断时抑郁之间的显著关联。与未接受认知行为疗法的患者相比，接受认知行为疗法的PTSD患者的PTSD症状有所改善。结论：PTSD在HNC患者中较为常见；然而，缺乏一种标准化的方法来诊断HNC患者和幸存者的创伤后应激障碍，这给确定可能从治疗中受益的患者带来了挑战。鉴于HNC是世界上第七大常见癌症，发病率不断增加，有必要更好地了解HNC和PTSD之间的关系，以便更好地筛查、识别和治疗PTSD，以改善患者与健康相关的生活质量，并提供最佳的患者护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current oncology ONCOLOGY-

CiteScore

3.30

自引率

7.70%

发文量

664

审稿时长

1 months

期刊介绍： Current Oncology is a peer-reviewed, Canadian-based and internationally respected journal. Current Oncology represents a multidisciplinary medium encompassing health care workers in the field of cancer therapy in Canada to report upon and to review progress in the management of this disease. We encourage submissions from all fields of cancer medicine, including radiation oncology, surgical oncology, medical oncology, pediatric oncology, pathology, and cancer rehabilitation and survivorship. Articles published in the journal typically contain information that is relevant directly to clinical oncology practice, and have clear potential for application to the current or future practice of cancer medicine.