New Curvularin and Norlignanolide Derivatives from Cocultures of Marine Mangrove Endophytic Fungus Penicillium brocae MA-231 and Phytopathogen Curvularia spicifera QA-26.

IF 2.3 3区化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Chemistry & Biodiversity Pub Date : 2025-03-25 DOI:10.1002/cbdv.202500761

Aoyuan Zhang, Xiaoshan Shi, Bingui Wang, Linghong Meng

引用次数: 0

Abstract

A new curvularin derivative, curvulone C (1) and a pair of new norlignanolide anomers, aspergilfuranone E (2) and 8-epi-aspergilfuranone E (3), together with six known secondary metabolites (4-9) were isolated and identified from the coculture of the marine mangrove endophytic fungus Penicillium brocae MA-231 and phytopathogen Curvularia spicifera QA-26. Their structures were elucidated on the basis of spectroscopic analysis, and the absolute configurations were assigned on the basis of TDDFT-ECD calculations. Compounds 1 and 4 showed inhibitory activities against several human and aquatic pathogens.

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来源期刊

Chemistry & Biodiversity 环境科学-化学综合

CiteScore

3.40

自引率

10.30%

发文量

475

审稿时长

2.6 months

期刊介绍： Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level. Since 2017, Chemistry & Biodiversity is published in an online-only format.