Development of a Sun Protection Factor for contact lenses (CL-SPF).

IF 2 Q2 OPHTHALMOLOGY
James S Wolffsohn, Tom Drew, Andrew Devitt, Sasha Kieran
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Abstract

Objective: Sun Protection Factor (SPF) of sunscreen products is well recognised by consumers. This study explored how SPF could be applied to ultraviolet radiation (UV) protection from contact lenses (CL-SPF).

Methods and analysis: UV transmission through 15 commercially available contact lenses and three spectacle lens materials was measured with a deuterium light source and spectrophotometer. CL-SPF values were calculated using the standard in vitro method used to test and label skin products. Ray tracing was applied to two sunglass designs to assess the effect of solar angle and head orientation on light reaching the ocular surface. Cellular damage profile of human corneal and conjunctival cells across the UV range was assessed in vitro to inform an SPF equivalent for CLs.

Results: CLs tested fell into three categories: CL-SPF with no UV blocker=1.0-2.0 (equivalent to using no sunscreen); CL-SPF with Class 2 UV blocker=12.3-24.8 (equivalent to SPF15); and CL-SPF with Class 1 UV blocker=59.6-66.2 (equivalent to SPF 50+). Despite the UV-blocking characteristics of sunglasses, ocular surface protection can be substantially reduced at certain solar angle and head orientation combinations; on average, 76%-89% of light was prevented from reaching the ocular surface depending on the intensity of the tint (80%-20% transmission). The data also suggest that cell damage and death of ocular surface cells has a similar profile to that of the skin, but conjunctival cells are more susceptible to UV damage.

Conclusion: CL-SPF is a viable metric to communicate the protection from the absorption/transmission of UV radiation that CLs offers wearers. However, a contact lens will only project the area of the ocular surface it covers, which is limited to mainly the cornea and internal eye tissues with soft CLs.

隐形眼镜防晒系数CL-SPF的研制
目的:防晒产品的防晒系数(SPF)得到消费者的认可。本研究探讨了如何将SPF应用于隐形眼镜的紫外线防护(CL-SPF)。方法与分析:用氘光源和分光光度计测量了15种市售隐形眼镜和3种眼镜镜片材料对紫外线的透射率。使用用于测试和标记皮肤产品的标准体外方法计算CL-SPF值。光线追踪应用于两种太阳镜设计,以评估太阳角度和头部方向对光到达眼表的影响。在体外评估了人类角膜和结膜细胞在紫外线范围内的细胞损伤情况,以确定CLs的等效SPF值。结果:测试的CLs分为三类:不使用紫外线阻隔剂的CL-SPF =1.0-2.0(相当于不使用防晒霜);2级防紫外线剂CL-SPF =12.3-24.8(相当于SPF15);1级防紫外线剂的CL-SPF =59.6-66.2(相当于spf50 +)。尽管太阳镜具有阻挡紫外线的特性,但在一定的太阳角度和头向组合下,对眼表的保护会大大降低;平均而言,76%-89%的光线被阻止到达眼表面,这取决于色调的强度(80%-20%的透射)。这些数据还表明,眼表细胞的细胞损伤和死亡与皮肤的细胞损伤和死亡具有相似的特征,但结膜细胞更容易受到紫外线的损伤。结论:CL-SPF是一种可行的指标,可以传达CLs为佩戴者提供的紫外线辐射吸收/透射保护。然而,隐形眼镜只能投射它所覆盖的眼表区域,这主要限于角膜和具有软CLs的内部眼组织。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Open Ophthalmology
BMJ Open Ophthalmology OPHTHALMOLOGY-
CiteScore
3.40
自引率
4.20%
发文量
104
审稿时长
20 weeks
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