Effectiveness of Titanium Occlusive Barriers in Guided Bone Regeneration: A Prospective Analysis of Vertical and Horizontal Bone Augmentation.

IF 3.9 3区医学 Q1 ENGINEERING, MULTIDISCIPLINARY

Biomimetics Pub Date : 2025-03-07 DOI:10.3390/biomimetics10030165

Luis Leiva-Gea, Paulino Sánchez-Palomino, Alfonso Lendínez-Jurado, María Daniela Corte-Torres, Isabel Leiva-Gea, Antonio Leiva-Gea

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Abstract

Background: Guided bone regeneration (GBR) is a widely used technique in oral and maxillofacial surgery to restore lost bone. The aim of this study is to evaluate the effectiveness of titanium occlusive barriers in GBR for increasing bone volume in both vertical and horizontal dimensions.

Methods: A prospective analysis was conducted on 11 patients (15 cases) undergoing bone augmentation with titanium barriers combined with bone graft biomaterials for dental implant placement. Bone gain was assessed using pre- and postoperative low-dose cone beam computed tomography (CBCT) measurements in vertical and horizontal planes. Histological analyses evaluated the quality and vascularization of the regenerated bone.

Results: Significant bone volume increases were observed, with a mean vertical gain of 7.60 mm (SD 0.23) and a horizontal gain of 5.44 mm (SD 0.39). Histological examination confirmed well-vascularized regenerated bone with minimal residual graft material, effective integration, and the formation of keratinized gingiva.

Conclusions: Titanium occlusive barriers in GBR provide a reliable and minimally invasive method for substantial bone regeneration, showing advantages such as ease of handling and reduced invasiveness. Additional studies are recommended to validate these findings and evaluate long-term outcomes.

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钛闭塞屏障在引导骨再生中的有效性：垂直和水平骨增强的前瞻性分析。

背景：引导下骨再生（GBR）是口腔颌面外科广泛使用的一种修复骨缺失的技术。本研究旨在评估钛闭塞屏障在 GBR 中增加垂直和水平方向骨量的有效性：方法：对 11 名患者（15 例）进行了前瞻性分析，这些患者在牙科植入物植入过程中使用钛屏障和骨移植生物材料进行骨增量。使用术前和术后低剂量锥形束计算机断层扫描（CBCT）测量垂直和水平平面的骨增量。组织学分析评估了再生骨的质量和血管化情况：结果：观察到骨量显著增加，垂直方向平均增加 7.60 毫米（SD 0.23），水平方向平均增加 5.44 毫米（SD 0.39）。组织学检查证实，再生骨血管良好，移植材料残留量极少，整合效果良好，并形成了角化的牙龈：结论：GBR 中的钛闭塞屏障为大量骨再生提供了一种可靠的微创方法，具有操作简便、创口小等优点。建议开展更多研究来验证这些发现并评估长期效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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