PREVENTION OF ALCOHOL-ASSOCIATED LIVER DISEASE.

IF 8 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Robyn Burton, Lorenzo Leggio, Alexandre Louvet, Nick Sheron, Ashwani K Singal
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引用次数: 0

Abstract

Abstract: Alcohol-associated liver disease (ALD) is the leading cause of morbidity, disease adjusted life-years lost, and mortality worldwide. The significant burden and cost to the healthcare systems from ALD is largely preventable, given that alcohol use is the most important determinant of risk and severity of ALD. In this article, we will review the emerging evidence for public health policies (minimum unit price of alcohol, limiting or banning alcohol advertising), aiming to reduce the availability of alcohol at the population level (primary prevention), preventing ALD especially advanced form of cirrhosis in at risk individuals (secondary prevention), and improving liver outcomes and long-term survival in patients with advanced ALD of cirrhosis and / or alcohol-associated hepatitis (tertiary prevention). We will highlight the critical role of clinicians in promoting the public health policies, widespread screening for AUD and for ALD, and integrating liver with addiction care for patients with ALD.

摘要:酒精相关性肝病(ALD)是全球发病率、疾病调整寿命损失和死亡率的主要原因。鉴于饮酒是导致 ALD 风险和严重程度的最重要决定因素,ALD 给医疗系统造成的巨大负担和成本在很大程度上是可以预防的。在本文中,我们将回顾公共卫生政策(酒精最低单价、限制或禁止酒精广告)的新证据,这些政策旨在减少酒精在人群中的供应(一级预防),预防 ALD,尤其是高危人群中的晚期肝硬化(二级预防),以及改善晚期 ALD 肝硬化和/或酒精相关肝炎患者的肝脏预后和长期生存(三级预防)。我们将强调临床医生在促进公共卫生政策、广泛开展 AUD 和 ALD 筛查以及整合 ALD 患者的肝脏和成瘾护理方面的关键作用。
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来源期刊
American Journal of Gastroenterology
American Journal of Gastroenterology 医学-胃肠肝病学
CiteScore
11.40
自引率
5.10%
发文量
458
审稿时长
12 months
期刊介绍: Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.
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