{"title":"Clinical Profile of High-Altitude Cerebral Edema: A Case Series.","authors":"Manish Bhartiya, Jatinder Kumar, Rahil Arora, Ankush Dhiman","doi":"10.4103/aian.aian_921_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>High-altitude cerebral edema (HACE) is a severe form of altitude sickness characterized by headache, ataxia, and altered consciousness. This study aims to describe the clinical features, radiological findings, and outcomes of patients diagnosed with HACE. This study was conducted at a tertiary care hospital in northeastern India. Eleven consecutive patients diagnosed with HACE based on clinical criteria were included. Clinical data, demographics, radiological findings, and outcome were collected. All 11 patients were young males. Headache was the most common symptom, followed by ataxia. Uncommon findings included retinal hemorrhages in two patients. Cytotoxic lesions of the corpus callosum were present in two patients, while one had micro-hemorrhages in the splenium. All the patients had a good outcome. HACE is a rare but serious condition that requires early recognition and treatment. Diagnosis is primarily clinical, and radiological findings may be normal in some cases.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Indian Academy of Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/aian.aian_921_24","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: High-altitude cerebral edema (HACE) is a severe form of altitude sickness characterized by headache, ataxia, and altered consciousness. This study aims to describe the clinical features, radiological findings, and outcomes of patients diagnosed with HACE. This study was conducted at a tertiary care hospital in northeastern India. Eleven consecutive patients diagnosed with HACE based on clinical criteria were included. Clinical data, demographics, radiological findings, and outcome were collected. All 11 patients were young males. Headache was the most common symptom, followed by ataxia. Uncommon findings included retinal hemorrhages in two patients. Cytotoxic lesions of the corpus callosum were present in two patients, while one had micro-hemorrhages in the splenium. All the patients had a good outcome. HACE is a rare but serious condition that requires early recognition and treatment. Diagnosis is primarily clinical, and radiological findings may be normal in some cases.
期刊介绍:
The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.