Clinical Profile of High-Altitude Cerebral Edema: A Case Series.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

Annals of Indian Academy of Neurology Pub Date : 2025-03-01 Epub Date: 2025-03-25 DOI:10.4103/aian.aian_921_24

Manish Bhartiya, Jatinder Kumar, Rahil Arora, Ankush Dhiman

引用次数: 0

Abstract

High-altitude cerebral edema (HACE) is a severe form of altitude sickness characterized by headache, ataxia, and altered consciousness. This study aims to describe the clinical features, radiological findings, and outcomes of patients diagnosed with HACE. This study was conducted at a tertiary care hospital in northeastern India. Eleven consecutive patients diagnosed with HACE based on clinical criteria were included. Clinical data, demographics, radiological findings, and outcome were collected. All 11 patients were young males. Headache was the most common symptom, followed by ataxia. Uncommon findings included retinal hemorrhages in two patients. Cytotoxic lesions of the corpus callosum were present in two patients, while one had micro-hemorrhages in the splenium. All the patients had a good outcome. HACE is a rare but serious condition that requires early recognition and treatment. Diagnosis is primarily clinical, and radiological findings may be normal in some cases.

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高原脑水肿的临床特征：一个病例系列。

摘要：高原脑水肿（high altitude cerebral edema， HACE）是一种以头痛、共济失调和意识改变为特征的严重高原反应。本研究旨在描述HACE患者的临床特征、影像学表现和预后。这项研究是在印度东北部的一家三级保健医院进行的。纳入了11例根据临床标准诊断为HACE的连续患者。收集临床资料、人口统计学、放射学结果和结果。11例患者均为年轻男性。头痛是最常见的症状，其次是共济失调。罕见的发现包括两名患者视网膜出血。2例胼胝体出现细胞毒性病变，1例脾微出血。所有患者预后良好。HACE是一种罕见但严重的疾病，需要早期识别和治疗。诊断主要是临床，在某些病例中放射学表现可能正常。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Indian Academy of Neurology Nervous System Diseases-

CiteScore

2.20

自引率

11.80%

发文量

293

审稿时长

29 weeks

期刊介绍： The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.