Huan Ling, Wenrui Zhang, Yunxiang Zhang, Jie Shen, Qian Liu
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引用次数: 0
Abstract
Lanthanide-doped upconversion nanoparticles (UCNPs) have recently demonstrated great promise in single-particle imaging (SPI) due to their exceptional photostability and minimal background fluorescence. However, their relatively dim brightness has posed a significant barrier to wider adoption in SPI applications. This review highlights recent advances in the application of UCNPs for SPI, focusing on strategies to enhance their brightness and reduce quenching effects in aqueous environments. Additionally, it summarizes the latest progress in employing UCNPs for single-particle tracking and super-resolution imaging, underscoring their potential in biomedical research. Finally, the review outlines current challenges and future directions in this field.
期刊介绍:
ChemBioChem (Impact Factor 2018: 2.641) publishes important breakthroughs across all areas at the interface of chemistry and biology, including the fields of chemical biology, bioorganic chemistry, bioinorganic chemistry, synthetic biology, biocatalysis, bionanotechnology, and biomaterials. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and supported by the Asian Chemical Editorial Society (ACES).