Silicocarnotite—A New Ceramic Material With Potential Application in Bone Tissue Regeneration

IF 3.9 3区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of biomedical materials research. Part A Pub Date : 2025-03-27 DOI:10.1002/jbm.a.37902

Patryk Romaniuk, Barbara Kołodziejska, Joanna Kolmas

{"title":"Silicocarnotite—A New Ceramic Material With Potential Application in Bone Tissue Regeneration","authors":"Patryk Romaniuk, Barbara Kołodziejska, Joanna Kolmas","doi":"10.1002/jbm.a.37902","DOIUrl":null,"url":null,"abstract":"<div>\n \n Silicocarnotite (Ca5(PO4)2(SiO4)) is an inorganic crystalline material classified as a silicophosphate. Its chemical composition is similar to that of calcium hydroxyapatite (Ca10(PO4)6(OH)2) and silicon-substituted hydroxyapatite (Ca10(PO4)6-x(SiO4)x(OH)2-x-□). Given the critical role of silicon ions in bone tissue metabolism, mineralization, and collagen synthesis, silicon-enriched hydroxyapatites have long been of significant interest in regenerative medicine. The natural presence of silicate ions in the structure of silicophosphates has prompted research into their synthesis and potential application as bone substitute materials in reconstructive and reparative bone surgery. This article reviews the current state of knowledge on silicocarnotite, including its physicochemical and biological properties, the application potential, and prospective research directions.\n </div>","PeriodicalId":15142,"journal":{"name":"Journal of biomedical materials research. Part A","volume":"113 4","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical materials research. Part A","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jbm.a.37902","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Silicocarnotite (Ca₅(PO₄)₂(SiO₄)) is an inorganic crystalline material classified as a silicophosphate. Its chemical composition is similar to that of calcium hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂) and silicon-substituted hydroxyapatite (Ca₁₀(PO₄)_6-x(SiO₄)_x(OH)_2-x-□). Given the critical role of silicon ions in bone tissue metabolism, mineralization, and collagen synthesis, silicon-enriched hydroxyapatites have long been of significant interest in regenerative medicine. The natural presence of silicate ions in the structure of silicophosphates has prompted research into their synthesis and potential application as bone substitute materials in reconstructive and reparative bone surgery. This article reviews the current state of knowledge on silicocarnotite, including its physicochemical and biological properties, the application potential, and prospective research directions.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of biomedical materials research. Part A 工程技术-材料科学：生物材料

CiteScore

10.40

自引率

2.00%

发文量

135

审稿时长

3.6 months

期刊介绍： The Journal of Biomedical Materials Research Part A is an international, interdisciplinary, English-language publication of original contributions concerning studies of the preparation, performance, and evaluation of biomaterials; the chemical, physical, toxicological, and mechanical behavior of materials in physiological environments; and the response of blood and tissues to biomaterials. The Journal publishes peer-reviewed articles on all relevant biomaterial topics including the science and technology of alloys,polymers, ceramics, and reprocessed animal and human tissues in surgery,dentistry, artificial organs, and other medical devices. The Journal also publishes articles in interdisciplinary areas such as tissue engineering and controlled release technology where biomaterials play a significant role in the performance of the medical device. The Journal of Biomedical Materials Research is the official journal of the Society for Biomaterials (USA), the Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Articles are welcomed from all scientists. Membership in the Society for Biomaterials is not a prerequisite for submission.