Health-promoting benefits of the wild mushroom Suillus mediterraneensis (Jacquet. & J. Blum) Redeuilh, collected from Algeria: Myco-chemical investigation and bioactive properties
{"title":"Health-promoting benefits of the wild mushroom Suillus mediterraneensis (Jacquet. & J. Blum) Redeuilh, collected from Algeria: Myco-chemical investigation and bioactive properties","authors":"Mimoune Souna, Choukri Tefiani, Tarik Mohammed Chaouche, Rachid Azzi, Salim Habi, Saliha Kermane Souna","doi":"10.1007/s11694-025-03111-1","DOIUrl":null,"url":null,"abstract":"<div><p><i>Suillus mediterraneensis</i> is a valuable resource, and its bioactive compounds and pharmacological activities provide a useful therapeutic ingredient. In this context, the present work focuses on the investigation of their mycochemical constituents in relation to their bioactive properties. Four extracts: hydro-methanolic, hexane, dichloromethane and mixture of solvents were examined. Cytotoxicity was tested as a first step to assess the safety using hemolytic test. The hydro-methanolic and mixture of solvents extracts contain powerful antioxidants as phenolic, flavonoid and condensed tannin (76.20 ± 5.47 and 59.53 ± 2.35 µg GAE/mg extract), (13.27 ± 1.39 and 9.11 ± 0.25 µg CE/mg extract) and (19.17 ± 2.89 and 18.92 ± 1.26 µg CE/mg extract) respectively. All extracts were found to have weak hemolytic actions. Hydro-methanolic extract displayed a high antioxidant property against DPPH (IC<sub>50</sub>: 50.56 ± 2.60 µg/mL) and ABTS (IC<sub>50</sub>: 44.53 ± 3.46 µg/mL). The mixture of solvents extract possessed better FRAP power (EC<sub>50</sub>: 89.67 ± 5.13 µg/mL), also it exerted the strongest anti-hemolytic potential (HT<sub>50</sub>: 192.44 ± 2.16 min at 200 µg/mL). The anti-inflammatory assay by inhibition of protein denaturation revealed that both extracts hydro-methanolic and mixture of solvents at 1500 μg/ml showed evidence of activity compared to diclofenac (71.37 ± 1.80%), (70.20 ± 1.80%) and (98.43 ± 0.52%) respectively. Heat-induced hemolysis assessed that hydro-methanolic, dichloromethane and mixture of solvents at 1000 μg/ml compared to acetyl salicylic acid demonstrated a promising protection (48.89 ± 1.10%), (46.28 ± 1.49%), (43.46 ± 3.67%) and (91.7 ± 0.99%) respectively. PCA and HCA analysis were applied in consideration of their bioactive compounds and biological abilities. The mixture of solvents and hydro-methanol extracts shows a promising anti-inflammatory and anti-hemolytic potential as one of the beneficial functions.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":631,"journal":{"name":"Journal of Food Measurement and Characterization","volume":"19 4","pages":"2276 - 2302"},"PeriodicalIF":2.9000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Food Measurement and Characterization","FirstCategoryId":"97","ListUrlMain":"https://link.springer.com/article/10.1007/s11694-025-03111-1","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Suillus mediterraneensis is a valuable resource, and its bioactive compounds and pharmacological activities provide a useful therapeutic ingredient. In this context, the present work focuses on the investigation of their mycochemical constituents in relation to their bioactive properties. Four extracts: hydro-methanolic, hexane, dichloromethane and mixture of solvents were examined. Cytotoxicity was tested as a first step to assess the safety using hemolytic test. The hydro-methanolic and mixture of solvents extracts contain powerful antioxidants as phenolic, flavonoid and condensed tannin (76.20 ± 5.47 and 59.53 ± 2.35 µg GAE/mg extract), (13.27 ± 1.39 and 9.11 ± 0.25 µg CE/mg extract) and (19.17 ± 2.89 and 18.92 ± 1.26 µg CE/mg extract) respectively. All extracts were found to have weak hemolytic actions. Hydro-methanolic extract displayed a high antioxidant property against DPPH (IC50: 50.56 ± 2.60 µg/mL) and ABTS (IC50: 44.53 ± 3.46 µg/mL). The mixture of solvents extract possessed better FRAP power (EC50: 89.67 ± 5.13 µg/mL), also it exerted the strongest anti-hemolytic potential (HT50: 192.44 ± 2.16 min at 200 µg/mL). The anti-inflammatory assay by inhibition of protein denaturation revealed that both extracts hydro-methanolic and mixture of solvents at 1500 μg/ml showed evidence of activity compared to diclofenac (71.37 ± 1.80%), (70.20 ± 1.80%) and (98.43 ± 0.52%) respectively. Heat-induced hemolysis assessed that hydro-methanolic, dichloromethane and mixture of solvents at 1000 μg/ml compared to acetyl salicylic acid demonstrated a promising protection (48.89 ± 1.10%), (46.28 ± 1.49%), (43.46 ± 3.67%) and (91.7 ± 0.99%) respectively. PCA and HCA analysis were applied in consideration of their bioactive compounds and biological abilities. The mixture of solvents and hydro-methanol extracts shows a promising anti-inflammatory and anti-hemolytic potential as one of the beneficial functions.
期刊介绍：
This interdisciplinary journal publishes new measurement results, characteristic properties, differentiating patterns, measurement methods and procedures for such purposes as food process innovation, product development, quality control, and safety assurance.
The journal encompasses all topics related to food property measurement and characterization, including all types of measured properties of food and food materials, features and patterns, measurement principles and techniques, development and evaluation of technologies, novel uses and applications, and industrial implementation of systems and procedures.
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