Emerging Trends in Fluorescent and Quenching Nanomaterials for Viral detection: Innovations in Biological and Chemical sensing

IF 4.1 Q1 CHEMISTRY, ANALYTICAL
Deeksha Nautiyal, Utkarsh Jain
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引用次数: 0

Abstract

Optical biosensors doped with nanomaterials are the most technologically advanced in viral diagnostics, showing higher sensitivity, specificity, and speed of detection. This review describes the role of fluorescent and quenching nanomaterials in the development of optical biosensing techniques. These sensors enable real-time, non-invasive viral detection with minimal preparation of samples by exploiting unique optical properties of nanomaterials, such as increased fluorescence, efficient energy transfer, and significant signal amplification. It is worth noting that the material's application in point-of-care settings effectively bridges laboratory accuracy with the practical applicability of real-world applications. Moreover, these aspects were put into review, along with the latest advancements in the emerging dual-functional nanocomposites able to integrate the fluorescence and quenching mechanisms for multimodal detection, with emphasis on what has been recently achieved and how these efforts have been developed to tackle stability, reproducibility, and scalability concerns. This will enable optical biosensing through advances in nanotechnology and pave the way for designing next-generation diagnostic platforms capable of addressing current and emerging viral threats.

Abstract Image

荧光和淬灭纳米材料用于病毒检测的新趋势:生物和化学传感的创新
掺杂纳米材料的光学生物传感器是病毒诊断中技术最先进的,具有更高的灵敏度、特异性和检测速度。本文综述了荧光纳米材料和猝灭纳米材料在光学生物传感技术发展中的作用。这些传感器利用纳米材料独特的光学特性(如增强的荧光、高效的能量转移和显著的信号放大),以最少的样品制备实现实时、非侵入性病毒检测。值得注意的是,该材料在护理点设置中的应用有效地将实验室准确性与现实世界应用的实际适用性联系起来。此外,对这些方面进行了回顾,以及新兴的双功能纳米复合材料的最新进展,这些复合材料能够集成多模态检测的荧光和猝灭机制,重点介绍了最近取得的成就,以及如何发展这些努力来解决稳定性、可重复性和可扩展性问题。这将通过纳米技术的进步实现光学生物传感,并为设计能够解决当前和新出现的病毒威胁的下一代诊断平台铺平道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Talanta Open
Talanta Open Chemistry-Analytical Chemistry
CiteScore
5.20
自引率
0.00%
发文量
86
审稿时长
49 days
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