Evaluating Associations Among Maternal ACEs, Perinatal Depression, and Infant Experiences of Adversity.

IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Samantha Addante, Lucia Ciciolla, Amanda Baraldi, Karina M Shreffler
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引用次数: 0

Abstract

Objective: The growing literature on the intergenerational transmission of childhood adversity highlights the need to identify potential mechanisms underlying the relationship between maternal and infant adversity. This study examines prenatal and postpartum depressive symptoms as mediators between maternal ACEs and postpartum infant experiences of adversity.

Methods: A diverse sample of 168 low-income, pregnant women (39% white) were recruited from urban prenatal clinics and followed for one-year post childbirth. Maternal childhood adversity and prenatal depressive symptoms were assessed during pregnancy, postpartum depressive symptoms were assessed at 6 months postpartum, and infant experiences of adversity at 12 months postpartum.

Results: The total indirect effect of maternal ACEs on infant experiences of adversity through prenatal and postpartum depressive symptoms was significant, indicating that these symptoms collectively mediate this relationship. Additionally, our results demonstrated a mediated pathway in which maternal ACEs contributed directly to prenatal depression, which in turn indirectly influenced postpartum depression and infant experiences of adversity.

Conclusion: Findings provide evidence for perinatal depressive symptoms as a potential mechanism that influences infant exposure to adverse experiences. Future research should explore these pathways in larger, more robust samples to clarify the role of postpartum depressive symptoms.

评价母亲不良经历、围产期抑郁和婴儿逆境经历之间的关系。
目的:越来越多的关于童年逆境代际传递的文献强调了确定母亲和婴儿逆境之间关系的潜在机制的必要性。本研究探讨了产前和产后抑郁症状在母亲ace与产后婴儿逆境经历之间的中介作用。方法:从城市产前诊所招募168名低收入孕妇(39%为白人),并在分娩后随访一年。在怀孕期间评估母亲童年逆境和产前抑郁症状,在产后6个月评估产后抑郁症状,在产后12个月评估婴儿逆境经历。结果:母亲不良经历通过产前和产后抑郁症状对婴儿逆境经历的间接影响显著,表明这些症状共同介导了这种关系。此外,我们的研究结果表明,母亲的不良经历直接导致产前抑郁,进而间接影响产后抑郁和婴儿的逆境经历。结论:研究结果为围产期抑郁症状作为影响婴儿不良经历暴露的潜在机制提供了证据。未来的研究应该在更大、更可靠的样本中探索这些途径,以阐明产后抑郁症状的作用。
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来源期刊
Maternal and Child Health Journal
Maternal and Child Health Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
3.20
自引率
4.30%
发文量
271
期刊介绍: Maternal and Child Health Journal is the first exclusive forum to advance the scientific and professional knowledge base of the maternal and child health (MCH) field. This bimonthly provides peer-reviewed papers addressing the following areas of MCH practice, policy, and research: MCH epidemiology, demography, and health status assessment Innovative MCH service initiatives Implementation of MCH programs MCH policy analysis and advocacy MCH professional development. Exploring the full spectrum of the MCH field, Maternal and Child Health Journal is an important tool for practitioners as well as academics in public health, obstetrics, gynecology, prenatal medicine, pediatrics, and neonatology. Sponsors include the Association of Maternal and Child Health Programs (AMCHP), the Association of Teachers of Maternal and Child Health (ATMCH), and CityMatCH.
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