{"title":"Drug-induced aseptic meningitis after amoxicillin use.","authors":"Jina Bai, Todd Cutler","doi":"10.1097/01.JAA.0000000000000198","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Drug-induced aseptic meningitis (DIAM) is a noninfectious meningitis related to a drug exposure. Diagnosis requires exclusion of infectious meningitis. Patients with DIAM will exhibit rapid improvement after discontinuation of the offending drug. Most patients will develop recurrent symptoms after repeat exposure to the offending agent. The clinical features of DIAM are indistinguishable from infectious meningitis and the recurrent symptoms often are identical to previous episodes of DIAM. Nonsteroidal anti-inflammatory drugs, co-trimoxazole, and penicillin are the medications that most commonly cause DIAM with use. This article describes a patient who was admitted to the hospital with meningoencephalitis after taking prophylactic amoxicillin for a dental procedure.</p>","PeriodicalId":48728,"journal":{"name":"Jaapa-Journal of the American Academy of Physician Assistants","volume":"38 4","pages":"29-31"},"PeriodicalIF":0.8000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jaapa-Journal of the American Academy of Physician Assistants","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/01.JAA.0000000000000198","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Drug-induced aseptic meningitis (DIAM) is a noninfectious meningitis related to a drug exposure. Diagnosis requires exclusion of infectious meningitis. Patients with DIAM will exhibit rapid improvement after discontinuation of the offending drug. Most patients will develop recurrent symptoms after repeat exposure to the offending agent. The clinical features of DIAM are indistinguishable from infectious meningitis and the recurrent symptoms often are identical to previous episodes of DIAM. Nonsteroidal anti-inflammatory drugs, co-trimoxazole, and penicillin are the medications that most commonly cause DIAM with use. This article describes a patient who was admitted to the hospital with meningoencephalitis after taking prophylactic amoxicillin for a dental procedure.
期刊介绍:
JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues.
Published monthly, JAAPA''s award-winning editorial includes:
-Clinical review articles (with AAPA-approved Category I CME in each issue)-
Case reports-
Clinical departments-
Original health services research-
Articles on issues of professional interest to PAs