Relationship between bleeding risk and arterial stiffness in patients with cerebral aneurysms.

IF 1.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Turkish Journal of Medical Sciences Pub Date : 2025-01-11 eCollection Date: 2025-01-01 DOI:10.55730/1300-0144.5959

Mehmet Selim Gel, Hasan Çağrı Postuk, İskender Samet Daltaban, Savaş Özer, Ercan Aydin, Emrah Keskin

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引用次数: 0

Abstract

Background/aim: A comprehensive risk factor assessment evaluating the susceptibility of cerebral aneurysms (CAs) to rupture has not yet been established. Therefore, the clinical management of unruptured CAs remains uncertain. This study aimed to assess whether arterial stiffness was associated with rupture risk in patients with CAs.

Materials and methods: Following magnetic resonance angiography, 49 patients with CAs and subarachnoid haemorrhage and ruptured CAs (confirmed via digital subtraction angiography) were included in the study. Arterial stiffness was measured using the VaSera VS-1000 vascular scanning system and expressed as cardio-ankle vascular index (CAVI) values. The CAVI values were compared between the patient groups.

Results: The mean age of the cerebrovascular aneurysm group was 51 ± 11 years, while that of the cerebrovascular aneurysmal haemorrhage group was 58 ± 12 (p = 0.308) years. Left and right CAVI values were significantly higher in the cerebrovascular aneurysm group (p < 0.05 for both). The CAVI values were positively correlated with haemorrhagic CA (p < 0.05).

Conclusion: This study revealed that increased arterial stiffness was associated with an increased risk of haemorrhage in patients with CAs. This result demonstrates the importance of evaluating arterial stiffness as an informative parameter for treatment and follow-up decisions in patients with CAs.

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脑动脉瘤患者出血风险与动脉僵化之间的关系。

背景/目的：评估脑动脉瘤（CA）破裂易感性的综合风险因素评估尚未确立。因此，对未破裂的 CA 的临床治疗仍不确定。本研究旨在评估动脉僵化与 CA 患者的破裂风险是否相关：在磁共振血管造影术后，49 名 CAs 和蛛网膜下腔出血以及 CAs 破裂（通过数字减影血管造影术确认）的患者被纳入研究。使用 VaSera VS-1000 血管扫描系统测量动脉僵化程度，并用心踝关节血管指数（CAVI）值表示。比较了不同患者组之间的 CAVI 值：结果：脑血管动脉瘤组的平均年龄为 51 ± 11 岁，而脑血管动脉瘤性出血组的平均年龄为 58 ± 12 岁（P = 0.308）。脑血管动脉瘤组的左侧和右侧 CAVI 值明显更高（均为 p <0.05）。CAVI值与出血性CA呈正相关（P < 0.05）：这项研究表明，动脉僵化的增加与 CA 患者出血风险的增加有关。这一结果表明，将动脉僵化度作为一个参考参数，对 CA 患者的治疗和随访决策具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Turkish Journal of Medical Sciences 医学-医学：内科

CiteScore

4.60

自引率

4.30%

发文量

143

审稿时长

3-8 weeks

期刊介绍： Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical details of a given medical subspeciality may not be evaluated for publication.