The Swiss Transplant Cohort Study: Implications for Transplant Infectious Diseases Research.

IF 2.6 4区医学 Q3 IMMUNOLOGY

Transplant Infectious Disease Pub Date : 2025-03-24 DOI:10.1111/tid.70023

Christian van Delden, Oriol Manuel, Cédric Hirzel, Laura N Walti, Nina Khanna, Hans H Hirsch, Neofytos Dionyios, Philipp Kohler, Irene A Abela, Nicolas J Mueller

引用次数: 0

Abstract

The longitudinal, nationwide Swiss Transplant Cohort Study (STCS) follows > 92% of all transplant recipients with comprehensive data collection tailored to overall and organ-specific transplant outcomes. Transplant infectious disease events are assembled under the auspices of transplant ID specialists using common definitions. With over 6000 active patients and a median follow-up exceeding 6 years, the cohort offers a unique platform for understanding real-world epidemiology in transplanted patients. Beyond observational analysis, the STCS supports randomized controlled trials to address specific research questions. This overview highlights the achievements of the STCS and explores its future directions.

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来源期刊

Transplant Infectious Disease 医学-传染病学

CiteScore

5.30

自引率

7.70%

发文量

210

审稿时长

4-8 weeks

期刊介绍： Transplant Infectious Disease has been established as a forum for presenting the most current information on the prevention and treatment of infection complicating organ and bone marrow transplantation. The point of view of the journal is that infection and allograft rejection (or graft-versus-host disease) are closely intertwined, and that advances in one area will have immediate consequences on the other. The interaction of the transplant recipient with potential microbial invaders, the impact of immunosuppressive strategies on this interaction, and the effects of cytokines, growth factors, and chemokines liberated during the course of infections, rejection, or graft-versus-host disease are central to the interests and mission of this journal. Transplant Infectious Disease is aimed at disseminating the latest information relevant to the infectious disease complications of transplantation to clinicians and scientists involved in bone marrow, kidney, liver, heart, lung, intestinal, and pancreatic transplantation. The infectious disease consequences and concerns regarding innovative transplant strategies, from novel immunosuppressive agents to xenotransplantation, are very much a concern of this journal. In addition, this journal feels a particular responsibility to inform primary care practitioners in the community, who increasingly are sharing the responsibility for the care of these patients, of the special considerations regarding the prevention and treatment of infection in transplant recipients. As exemplified by the international editorial board, articles are sought throughout the world that address both general issues and those of a more restricted geographic import.