Incidence and risk factors of delayed facial paralysis after vestibular schwannoma resection: A systematic review and meta-analysis.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

World neurosurgery Pub Date : 2025-03-22 DOI:10.1016/j.wneu.2025.123938

Xiezhuo Zhang, Hongbo Wen, Guohuan Chen

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引用次数: 0

Abstract

Objective: Delayed facial nerve paralysis (DFNP) is a common complication after vestibular schwannoma surgery. Previous studies have focused on immediate FNP, and the risk factors for developing DFNP remain largely unclear. This study aimed to determine the incidence and risk factors of DFNP in patients after vestibular schwannoma resection.

Materials and method: Up to 8 October 2024, PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, and China Science and Technology Journal Database (VIP database) were searched to extract the related data of DFNP. The pooled incidence of DFNP was calculated. Possible risk factors of DFNP were conducted to report the odds ratio (OR)/weighted mean difference (WMD), and their 95% confidence intervals (CIs).

Results: Twenty-seven studies were included, and 8,656 patients underwent vestibular schwannoma resection. The incidence of DFNP in patients with vestibular schwannoma who underwent microsurgical resection was 12.3% (95%CI: 9.4%, 15.1%). The results of the influencing factor analysis showed that age (WMD: -4.28, 95%CI: -5.66, -2.91) and tumor size (WMD: 0.17, 95%CI: 0.01, 0.22) were related to the incidence of DFNP in patients after vestibular schwannoma resection.

Conclusion: DFNP is a complication after vestibular schwannoma surgery that cannot be ignored. The risk factors (age and tumor size) of DFNP in patients after vestibular schwannoma surgery still need to be considered, and clinical management of high-risk groups should be strengthened in clinical practice.

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来源期刊

World neurosurgery CLINICAL NEUROLOGY-SURGERY

CiteScore

3.90

自引率

15.00%

发文量

1765

审稿时长

47 days

期刊介绍： World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The journal''s mission is to: -To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care. -To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide. -To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients. Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS