Associations of moderate-to-vigorous physical activity and sitting time with risk of disability and mortality among Japanese older adults.

IF 3.7 2区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Journal of Epidemiology Pub Date : 2025-03-22 DOI:10.2188/jea.JE20240385

Daiki Watanabe, Tsukasa Yoshida, Yuya Watanabe, Yosuke Yamada, Motohiko Miyachi, Misaka Kimura

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引用次数: 0

Abstract

Background: The interaction and substitution effects of physical activity (PA) and sitting time (ST) living in non-western countries have not been well investigated. This study aimed to examine the association of moderate-to-vigorous physical activity (MVPA) and ST with disability and mortality in older adults.

Methods: This prospective study analyzed data from 10,164 adults over 65 who participated in the Kyoto-Kameoka study in Japan. We evaluated MVPA and ST using the validated International Physical Activity Questionnaire-Short Form. Participants were categorized into four groups based on their levels of MVPA (150 min/week) and ST (300 min/day): low MVPA/high ST, low MVPA/low ST, high MVPA/high ST, and high MVPA/low ST. Outcomes were gathered between July 30, 2011, and November 30, 2016.

Results: Over a median follow-up of 5.3 years (45,461 person-years), 2,273 disability cases were documented. The low MVPA/high ST groups were associated with higher disability risk than those in the high MVPA/low ST groups (hazard ratios [HRs], 1.52; 95% confidence interval [CI], 1.31-1.75), and the interaction between MVPA and ST accounted for 48.5% of the relative excess risk of disability in the low MVPA/high ST group (p for interaction = 0.006). Replacing daily 10 min of ST with 10 min of MVPA was associated with a reduced risk of disability (HR, 0.980; 95% CI, 0.971-0.989) and all-cause mortality (HR, 0.975; 95% CI, 0.962-0.988).

Conclusions: These findings indicate that even a small substitution of ST with MVPA could help lower both the risk of disability and mortality.

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日本老年人中高强度体育活动和久坐时间与残疾和死亡风险的关系

背景：在非西方国家，身体活动（PA）和坐着时间（ST）的相互作用和替代效应尚未得到很好的研究。本研究旨在探讨中高强度体育活动（MVPA）和ST与老年人残疾和死亡率的关系。方法：这项前瞻性研究分析了10164名参加日本京都-龟冈研究的65岁以上成年人的数据。我们使用经过验证的国际体育活动问卷-短表格评估MVPA和ST。参与者根据他们的MVPA（150分钟/周）和ST（300分钟/天）水平分为四组：低MVPA/高ST，低MVPA/低ST，高MVPA/高ST和高MVPA/低ST。结果：中位随访5.3年（45,461人年），记录了2,273例残疾病例。与高MVPA/低ST组相比，低MVPA/高ST组与更高的残疾风险相关(危险比[hr]， 1.52；95%可信区间[CI]， 1.31-1.75)， MVPA和ST之间的相互作用占低MVPA/高ST组相对超额致残风险的48.5%（相互作用p = 0.006）。将每日10分钟ST替换为10分钟MVPA与残疾风险降低相关(HR, 0.980；95% CI, 0.971-0.989)和全因死亡率(HR, 0.975；95% ci, 0.962-0.988)。结论：这些发现表明，即使用MVPA代替ST，也可以帮助降低致残和死亡率的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Epidemiology 医学-公共卫生、环境卫生与职业卫生

CiteScore

7.50

自引率

4.30%

发文量

172

审稿时长

6-12 weeks

期刊介绍： The Journal of Epidemiology is the official open access scientific journal of the Japan Epidemiological Association. The Journal publishes a broad range of original research on epidemiology as it relates to human health, and aims to promote communication among those engaged in the field of epidemiological research and those who use epidemiological findings.