{"title":"A Case of Thyrotoxicosis and Excess Iodine Due to Habitual Use of Polyvinylpyrrolidone Iodine while Gargling in an Iodine-sufficient Area.","authors":"Kanako Sato, Hiroaki Asai, Saori Yoshioka, Keisuke Murakawa, Hiroyuki Sho, Ryoko Inui, Motohiro Kosugi, Yoji Hazama, Tetsuyuki Yasuda","doi":"10.2169/internalmedicine.4868-24","DOIUrl":null,"url":null,"abstract":"<p><p>Excess iodine can influence the pathophysiology of the thyroid gland and results of various thyroid-related examinations. We herein report a 60-year-old Japanese man with thyrotoxicosis and excess iodine due to habitual use of polyvinylpyrrolidone iodine (PVP-I) to gargle for 20 years. Initial laboratory and imaging findings were suggestive of painless thyroiditis. However, after cessation of PVP-I use for gargling, these results changed to findings suggestive of Graves' disease, with worsening thyrotoxicosis. A detailed questionnaire regarding excess iodine is important for the accurate diagnosis of thyrotoxicosis, even in patients living in iodine-sufficient areas where iodine-induced thyrotoxicosis is rare.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internal Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2169/internalmedicine.4868-24","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Excess iodine can influence the pathophysiology of the thyroid gland and results of various thyroid-related examinations. We herein report a 60-year-old Japanese man with thyrotoxicosis and excess iodine due to habitual use of polyvinylpyrrolidone iodine (PVP-I) to gargle for 20 years. Initial laboratory and imaging findings were suggestive of painless thyroiditis. However, after cessation of PVP-I use for gargling, these results changed to findings suggestive of Graves' disease, with worsening thyrotoxicosis. A detailed questionnaire regarding excess iodine is important for the accurate diagnosis of thyrotoxicosis, even in patients living in iodine-sufficient areas where iodine-induced thyrotoxicosis is rare.
期刊介绍:
Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine.
Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.