Case report: Endolymphatic system disease in elasmobranchs: clinical presentation, diagnosis, and treatment strategies.

IF 2.6 2区 农林科学 Q1 VETERINARY SCIENCES
Frontiers in Veterinary Science Pub Date : 2025-03-10 eCollection Date: 2024-01-01 DOI:10.3389/fvets.2024.1463428
Whitney Greene, Nuno Pereira, Bethany Doescher, Carlos Rojo-Solis, Hugo David, Ricardo Faustino, David Reese, Ryan De Voe, Ed Latson, Natalie Mylniczenko
{"title":"Case report: Endolymphatic system disease in elasmobranchs: clinical presentation, diagnosis, and treatment strategies.","authors":"Whitney Greene, Nuno Pereira, Bethany Doescher, Carlos Rojo-Solis, Hugo David, Ricardo Faustino, David Reese, Ryan De Voe, Ed Latson, Natalie Mylniczenko","doi":"10.3389/fvets.2024.1463428","DOIUrl":null,"url":null,"abstract":"<p><p>The inner ear is an often overlooked system in elasmobranchs with few documented reports of disease or other abnormalities in the literature. Similar to terrestrial vertebrates, it is located in the cranium, and there are multiple components to the ear of elasmobranchs including a pair of membranous labyrinths each with three semicircular canals and four chambers or end organs (the saccule, the lagena, the utricle and the macula neglecta) making up the endolymphatic system (ELS). There is species variability among the inner ear anatomy of elasmobranchs, and this may play a role in disease development, progression, and treatment outcomes. Also similar to terrestrial vertebrates, this system plays a key role in hearing, acceleration, and orientation. When affected, clinical signs may include localized areas of swelling or stoma development along the dorsal midline of the head at the endolymphatic pores, atypical swimming behaviors consistent with vestibular disease (spiraling/spinning or barrel rolling, or tilting to one side), and anorexia. Less frequently, the eyes may also be affected and present with exophthalmia, hyphema, and/or panophthalmitis. Herein are case series from five institutions representing a variety of elasmobranch species affected with ELS disease with discussion of anatomy, clinical presentation, diagnostics, etiology, treatment, and outcomes. Endolymphatic disease may be clinically underdiagnosed in elasmobranchs and mistaken for other diseases such as superficial subcutaneous or subdermal abscesses, focal dermatitis, or neuropathies presumed to not be associated with the inner ear system. In addition, disease may be occult for a long period of time prior to overt manifestation of signs or chronic with waxing and waning clinical signs, likely because of anatomy and resultant treatment challenges. Awareness and additional research may help to promote timely identification, improve diagnostic and treatment options, and help to optimize individual animal welfare.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"11 ","pages":"1463428"},"PeriodicalIF":2.6000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931651/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Veterinary Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fvets.2024.1463428","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

The inner ear is an often overlooked system in elasmobranchs with few documented reports of disease or other abnormalities in the literature. Similar to terrestrial vertebrates, it is located in the cranium, and there are multiple components to the ear of elasmobranchs including a pair of membranous labyrinths each with three semicircular canals and four chambers or end organs (the saccule, the lagena, the utricle and the macula neglecta) making up the endolymphatic system (ELS). There is species variability among the inner ear anatomy of elasmobranchs, and this may play a role in disease development, progression, and treatment outcomes. Also similar to terrestrial vertebrates, this system plays a key role in hearing, acceleration, and orientation. When affected, clinical signs may include localized areas of swelling or stoma development along the dorsal midline of the head at the endolymphatic pores, atypical swimming behaviors consistent with vestibular disease (spiraling/spinning or barrel rolling, or tilting to one side), and anorexia. Less frequently, the eyes may also be affected and present with exophthalmia, hyphema, and/or panophthalmitis. Herein are case series from five institutions representing a variety of elasmobranch species affected with ELS disease with discussion of anatomy, clinical presentation, diagnostics, etiology, treatment, and outcomes. Endolymphatic disease may be clinically underdiagnosed in elasmobranchs and mistaken for other diseases such as superficial subcutaneous or subdermal abscesses, focal dermatitis, or neuropathies presumed to not be associated with the inner ear system. In addition, disease may be occult for a long period of time prior to overt manifestation of signs or chronic with waxing and waning clinical signs, likely because of anatomy and resultant treatment challenges. Awareness and additional research may help to promote timely identification, improve diagnostic and treatment options, and help to optimize individual animal welfare.

求助全文
约1分钟内获得全文 求助全文
来源期刊
Frontiers in Veterinary Science
Frontiers in Veterinary Science Veterinary-General Veterinary
CiteScore
4.80
自引率
9.40%
发文量
1870
审稿时长
14 weeks
期刊介绍: Frontiers in Veterinary Science is a global, peer-reviewed, Open Access journal that bridges animal and human health, brings a comparative approach to medical and surgical challenges, and advances innovative biotechnology and therapy. Veterinary research today is interdisciplinary, collaborative, and socially relevant, transforming how we understand and investigate animal health and disease. Fundamental research in emerging infectious diseases, predictive genomics, stem cell therapy, and translational modelling is grounded within the integrative social context of public and environmental health, wildlife conservation, novel biomarkers, societal well-being, and cutting-edge clinical practice and specialization. Frontiers in Veterinary Science brings a 21st-century approach—networked, collaborative, and Open Access—to communicate this progress and innovation to both the specialist and to the wider audience of readers in the field. Frontiers in Veterinary Science publishes articles on outstanding discoveries across a wide spectrum of translational, foundational, and clinical research. The journal''s mission is to bring all relevant veterinary sciences together on a single platform with the goal of improving animal and human health.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信