Respiratory modulation of beta corticomuscular coherence in isometric hand movements.

Abstract

Respiration is a fundamental physiological function in humans, often synchronized with movement to enhance performance and efficiency. Recent studies have underscored the modulatory effects of respiratory rhythms on brain oscillations and various behavioral responses, including sensorimotor processes. In light of this connection, our study aimed to investigate the influence of different respiratory patterns on beta corticomuscular coherence (CMC) during isometric hand flexion and extension. Utilizing electroencephalogram (EEG) and surface electromyography (sEMG), we examined three breathing conditions: normal breathing, deep inspiration, and deep expiration. Two experimental protocols were employed: the first experiment required participants to simultaneously breathe and exert force, while the other involved maintaining a constant force while varying breathing patterns. The results revealed that deep inspiration significantly enhanced beta CMC during respiration-synchronized tasks, whereas normal breathing resulted in higher CMC compared to deep respiration during sustained force exertion. In the second experiment, beta CMC was cyclically modulated by respiratory phase across all breathing conditions. The difference in the outcomes from the two protocols demonstrated a task-specific modulation of respiration on motor control. Overall, these findings indicate the complex dynamics of respiration-related effects on corticomuscular neural communication and provide valuable insights into the mechanisms underpinning the coupling between respiration and motor function.

Supplementary information: The online version contains supplementary material available at 10.1007/s11571-025-10245-x.