Correction to “Zerumbone, a ginger sesquiterpene, inhibits migration, invasion, and metastatic behavior of human malignant glioblastoma multiforme in vitro”

IF 5 3区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

BioFactors Pub Date : 2025-03-26 DOI:10.1002/biof.70010

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引用次数: 0

Abstract

Jalili-Nik M, Afshari AR, Sabri H, Bibak B, Mollazadeh H, Sahebkar A. Zerumbone, a ginger sesquiterpene, inhibits migration, invasion, and metastatic behavior of human malignant glioblastoma multiforme in vitro. BioFactors. 2021;47:729–39. https://doi.org/10.1002/biof.1756

The initial submission of this article presented Figure 4 derived from a scanned gel image that was cropped to focus on specific bands. This resulted in concerns regarding the verifiability of the original data. To rectify this issue, the authors have revised the figures in the article to include data from replicates for which source data is available. This updated analysis encompasses results from three independent experiments, which clearly demonstrate that the reduction in MMPs' activity with increasing dosages of Zerumbone is consistently replicated across these experiments. Importantly, the overall significance of the new reanalysis remains consistent with the initial findings, adequately addressing the editors' concerns. The authors ensure the integrity of their published work.

Abstract Image

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更正“Zerumbone，一种生姜倍半萜，在体外抑制人类多形性恶性胶质母细胞瘤的迁移、侵袭和转移行为”

Jalili-Nik M, Afshari AR, Sabri H, Bibak B, Mollazadeh H, Sahebkar a .生姜倍半萜对人多形性恶性胶质母细胞瘤迁移、侵袭和转移行为的体外抑制作用。BioFactors。2021; 47:729-39。https://doi.org/10.1002/biof.1756The本文最初提交的图4来自于扫描的凝胶图像，该图像被裁剪以聚焦于特定波段。这导致了对原始数据的可核查性的关注。为了纠正这个问题，作者修改了文章中的数字，以包括可获得源数据的复制数据。这一最新分析包含了三个独立实验的结果，这些实验清楚地表明，随着Zerumbone剂量的增加，MMPs活性的降低在这些实验中得到了一致的复制。重要的是，新的重新分析的总体意义与最初的发现保持一致，充分解决了编辑的担忧。作者确保其发表作品的完整性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BioFactors 生物-内分泌学与代谢

CiteScore

11.50

自引率

3.30%

发文量

审稿时长

6-12 weeks

期刊介绍： BioFactors, a journal of the International Union of Biochemistry and Molecular Biology, is devoted to the rapid publication of highly significant original research articles and reviews in experimental biology in health and disease. The word “biofactors” refers to the many compounds that regulate biological functions. Biological factors comprise many molecules produced or modified by living organisms, and present in many essential systems like the blood, the nervous or immunological systems. A non-exhaustive list of biological factors includes neurotransmitters, cytokines, chemokines, hormones, coagulation factors, transcription factors, signaling molecules, receptor ligands and many more. In the group of biofactors we can accommodate several classical molecules not synthetized in the body such as vitamins, micronutrients or essential trace elements. In keeping with this unified view of biochemistry, BioFactors publishes research dealing with the identification of new substances and the elucidation of their functions at the biophysical, biochemical, cellular and human level as well as studies revealing novel functions of already known biofactors. The journal encourages the submission of studies that use biochemistry, biophysics, cell and molecular biology and/or cell signaling approaches.