Clinical Efficacy of CGF Combined With Periodic Supramolecular Salicylic Acid in the Treatment of Chloasma

IF 2.3 4区医学 Q2 DERMATOLOGY

Journal of Cosmetic Dermatology Pub Date : 2025-03-26 DOI:10.1111/jocd.70146

Ge Su, Qiang Fu, Xun Zhou

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引用次数: 0

Abstract

Objective

To investigate the clinical efficacy of CGF combined with supramolecular salicylic acid cycle injection for melasma.

Methods

Twenty patients with chloasma admitted to our hospital were selected and treated with CGF facial injection. After each CGF injection, supramolecular salicylic acid was given once. After one cycle of treatment, the severity of melasma and skin parameters before and after treatment were compared using the modified melasma Area and Severity index (MASI) and VISIA facial image analysis system, respectively. At the same time, the patients' self-satisfaction was investigated.

Results

The total effective rate of CGF combined with supramolecular salicylic acid in the treatment of chloasma was 95%. Compared with before treatment, the VISIA scores in spots, UV spots, brown spots, red areas, wrinkles, texture, pore and porphyrins scores were significantly increased after treatment. After CGF combined with supramolecular salicylic acid treatment, the MASI score of chloasma patients was significantly reduced (4.70 ± 2.47 vs. 15.30 ± 4.01, p < 0.001). The results showed that the total satisfaction of patients with facial skin improvement after CGF combined with supramolecular salicylic acid treatment was 95.00%.

Conclusion

CGF combined with supramolecular salicylic acid has an obvious effect on the comprehensive overall improvement of melasma and facial aging patients, and can effectively accelerate the speed of skin lesion repair and pigment elimination, which is worthy of clinical promotion and application.

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来源期刊

Journal of Cosmetic Dermatology DERMATOLOGY-

CiteScore

4.30

自引率

13.00%

发文量

818

审稿时长

>12 weeks

期刊介绍： The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.