Toxicity of environmentally relevant concentration of esfenvalerate and Taraxacum officinale application to overcome toxicity: A multi-bioindicator in-vivo study

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution Pub Date : 2025-03-24 DOI:10.1016/j.envpol.2025.126111

Fatih Kutluer , İlknur Güç , Emine Yalçın , Kültiğin Çavuşoğlu

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Abstract

The present study aimed to investigate the toxic effects of environmentally relevant concentrations of esfenvalerate on non-target organisms and the potential toxicity-reducing role of Taraxacum officinale extract (Toex). Esfenvalerate concentration measured as 0.8 μg L⁻¹ in Pazarsuyu stream, which is also used in agricultural irrigation in Giresun-Bulancak region, was used as environmentally relevant concentration. 0.8 μg L⁻¹ esfenvalerate resulted in a reduction in the mitotic index, levels of chlorophyll a and b, as well as root elongation, germination and weight gain in the bioindicator organism Allium cepa. Esfenvalerate treatment resulted in an increase in the frequency of chromosomal abnormalities, as well as the induction of O₂^•– formation and oxidative stress, which was evidenced by an elevation in the levels of proline and malondialdehyde. Following treatment with 0.8 μg L⁻¹ esfenvalerate, the percentage of tail DNA was 83.6 %, with a concomitant increase in cell death of 77.4 % in comparison to the control. In addition to determining the toxic effects of insecticides on non-target organisms, the solutions to be developed against these toxic effects are also very valuable. For this purpose, the protective properties of Toex were tested against the toxicity induced by esfenvalerate. The application of 7 mg L⁻¹ Toex together with esfenvalerate provided 48.88 % protection in germination percentage, 28.61 % protection in cell proliferation, 37.14 % protection in sticky chromosome, and 58.7 % protection in cell death. In conclusion, the use of insecticides has been demonstrated to have adverse effects on non-target organisms. Comprehensive toxicity testing represents a valuable resource for the effective management of insecticide risks. Furthermore, the investigation and identification of solutions to problems enhances the value of the effort expended. In this study, Toex provided high protection against esfenvalerate, which has been shown to induce oxidative stress and other toxic effects.

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环境相关浓度的埃斯氰戊酸和蒲鲁英应用对克服毒性的毒性：一项多生物指标的体内研究

本研究旨在调查环境相关浓度的艾司氰戊菊酯对非目标生物的毒性影响，以及蒲公英提取物（Toxx）的潜在减毒作用。在 Pazarsuyu 溪流中测得的艾司氰戊菊酯浓度为 0.8 μg L-1，该溪流也用于吉雷松-布兰卡克地区的农业灌溉。0.8 μg L-1 的甲氰戊菊酯会导致生物指标生物薤白的有丝分裂指数、叶绿素 a 和叶绿素 b 水平以及根的伸长、发芽和增重下降。艾司戊酸处理会增加染色体异常的频率，并诱导氧气的形成和氧化应激，这表现在脯氨酸和丙二醛水平的升高。用 0.8 μg L-1 的甲氰戊菊酯处理后，尾部 DNA 的比例为 83.6%，与对照组相比，细胞死亡率增加了 77.4%。除了确定杀虫剂对非目标生物的毒性作用外，针对这些毒性作用开发的解决方案也非常有价值。为此，我们测试了 Toex 的保护特性是否能抵御甲氰戊菊酯的毒性。在施用 7 mg L-1 的托埃克斯和甲氰戊菊酯的同时，对发芽率的保护率为 48.88%，对细胞增殖的保护率为 28.61%，对染色体粘连的保护率为 37.14%，对细胞死亡的保护率为 58.7%。总之，杀虫剂的使用已被证明会对非目标生物产生不利影响。全面的毒性测试是有效管理杀虫剂风险的宝贵资源。此外，调查和确定问题的解决方案也提高了所付出努力的价值。在这项研究中，Toex 对艾司氰戊菊酯具有很强的保护作用，而艾司氰戊菊酯已被证明会诱发氧化应激和其他毒性作用。

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来源期刊

Environmental Pollution 环境科学-环境科学

CiteScore

16.00

自引率

6.70%

发文量

2082

审稿时长

2.9 months

期刊介绍： Environmental Pollution is an international peer-reviewed journal that publishes high-quality research papers and review articles covering all aspects of environmental pollution and its impacts on ecosystems and human health. Subject areas include, but are not limited to: • Sources and occurrences of pollutants that are clearly defined and measured in environmental compartments, food and food-related items, and human bodies; • Interlinks between contaminant exposure and biological, ecological, and human health effects, including those of climate change; • Contaminants of emerging concerns (including but not limited to antibiotic resistant microorganisms or genes, microplastics/nanoplastics, electronic wastes, light, and noise) and/or their biological, ecological, or human health effects; • Laboratory and field studies on the remediation/mitigation of environmental pollution via new techniques and with clear links to biological, ecological, or human health effects; • Modeling of pollution processes, patterns, or trends that is of clear environmental and/or human health interest; • New techniques that measure and examine environmental occurrences, transport, behavior, and effects of pollutants within the environment or the laboratory, provided that they can be clearly used to address problems within regional or global environmental compartments.