Mack C. Mitchell, Brian P. Lee, Jessica Mellinger, Laura E. Nagy
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引用次数: 0
Abstract
We thank Kang for their comments on our recent Consensus Statement (Lee, B. P. et al. Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement. Nat. Rev. Gastroenterol. Hepatol. 21, 626–645 (2024))1 to incorporate genetic variations into consideration (Kang, B. Incorporating genetic variations in alcohol-associated liver disease trials for East Asian populations. Nat. Rev. Gastroenterol. Hepatol. https://doi.org/10.1038/s41575-025-01060-0 (2025))2. We agree that people who are deficient in ALDH2 and drink alcohol might be at increased risk of cancer of the upper digestive tract, oesophagus and liver. The increased risk of cancer in those who are ALDH2-deficient noted by Kang was not the focus of our initiative, but we appreciate the acknowledgement of the increased risk for this population.
期刊介绍：
Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication.
The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information.
Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.
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