Reply to ‘Incorporating genetic variations in alcohol-associated liver disease trials for East Asian populations’

IF 51 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Nature Reviews Gastroenterology &Hepatology Pub Date : 2025-03-24 DOI:10.1038/s41575-025-01059-7

Mack C. Mitchell, Brian P. Lee, Jessica Mellinger, Laura E. Nagy

引用次数: 0

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回复“将遗传变异纳入东亚人群酒精相关肝病试验”

我们感谢Kang对我们最近的共识声明（Lee, b.p. et al.）的评论。设计临床试验以解决酒精使用和酒精相关肝病：专家小组共识声明。Nat Rev. Gastroenterol。国际肝病杂志，21,626-645(2024))1纳入遗传变异考虑(Kang， B.纳入东亚人群酒精相关肝病试验的遗传变异。Nat Rev. Gastroenterol。乙醇。https://doi.org/10.1038/s41575 - 025 - 01060 - 0(2025)) 2。我们同意，缺乏ALDH2并饮酒的人患上消化道、食道癌和肝癌的风险可能会增加。Kang指出的aldh2缺陷患者癌症风险的增加并不是我们研究的重点，但我们对这一人群风险增加的认识表示赞赏。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Gastroenterology &Hepatology 医学-胃肠肝病学

CiteScore

52.30

自引率

0.60%

发文量

147

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.